Showing results 1 to 60 of 61
A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis Lee, Eunbeol; Jung, Yeon-Joo; Park, Yu Rim; Lim, Seongjoon; Choi, Young-Jin; Lee, Se Young; Kim, Chan Hyuk; et al, NATURE AGING, v.2, no.8, pp.726 - 741, 2022-08 |
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes Karottki, Karen Julie la Cour; Hefzi, Hooman; Li, Songyuan; Pedersen, Lasse Ebdrup; Spahn, Philipp N.; Joshi, Chintan; Ruckerbauer, David; et al, METABOLIC ENGINEERING, v.66, pp.114 - 122, 2021-07 |
A novel fabrication method of macroporous biodegradable polymer scaffolds using gas foaming salt as a porogen additive Nam, Yoon Sung; Yoon, Jun Jin; Park, Tae Gwan, JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, v.53, no.1, pp.1 - 7, 2000 |
A Six-well Plate Method: Less Laborious and Effective Method for Cultivation of Obligate Anaerobic Microorganisms Nakamura, Kohei; Tamaki, Hideyuki; Kang, Myung Suk; Mochimaru, Hanako; Lee, Sung Taik; Nakamura, Kazunori; Kamagata, Yoichi, MICROBES AND ENVIRONMENTS, v.26, no.4, pp.301 - 306, 2011-12 |
Aberrant methylation of donor genome in cloned bovine embryos Kang, Yong-Kook; Koo, Deog-Bon; Park, Jung-Sun; Choi, Young-Hee; Chung, An Sik; Lee, Kyung-Kwang; Han, Yong Mahn, NATURE GENETICS, v.28, no.2, pp.173 - 177, 2001-06 |
Anti-cell death engineering of CHO cells: Co-overexpression of Bcl-2 for apoptosis inhibition, Beclin-1 for autophagy induction Lee, Jae-Seong; Ha, Tae-Kwang; Park, Jin-Hyoung; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.110, no.8, pp.2195 - 2207, 2013-08 |
Artificial transcription factors increase production of recombinant antibodies in Chinese hamster ovary cells Kwon, RJ; Kim, S; Lee, SI; Hwang, SJ; Lee, Gyun-Min; Kim, JS; Seol, W, BIOTECHNOLOGY LETTERS, v.28, pp.9 - 15, 2006-01 |
Bacterial community structure in activated sludge reactors treating free or metal-complexed cyanides Quan, ZX; Rhee, SK; Bae, JW; Baek, JH; Park, YH; Lee, Sung Taik, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.16, pp.232 - 239, 2006-02 |
Bcl-2 overexpression in CHO cells improves polyethylenimine-mediated gene transfection Lee, So-Jeong; Lee, Gyun-Min, PROCESS BIOCHEMISTRY, v.48, no.9, pp.1436 - 1440, 2013-09 |
Biodegradable PLGA microcarriers for injectable delivery of chondrocytes: Effect of surface modification on cell attachment and function Chun, KW; Yoo, HS; Yoon, JJ; Park, TG, BIOTECHNOLOGY PROGRESS, v.20, no.6, pp.1797 - 1801, 2004 |
Characterization and Expression of Proprotein Convertases in CHO Cells: Efficient Proteolytic Maturation of Human Bone Morphogenetic Protein-7 Sathya Murthy, Madhavi; Kim, Che Lin; Bang, You Lim; Kim, Young Sik; Jang, Ju Woong; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.112, no.3, pp.560 - 568, 2015-03 |
Characterization of chimeric antibody producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure Kim, SJ; Kim, NS; Ryu, CJ; Hong, HJ; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.58, no.1, pp.73 - 84, 1998-04 |
Chemical Inhibition of Autophagy: Examining Its Potential to Increase the Specific Productivity of Recombinant CHO Cell Lines Baek, Eric H; Kim, Che Lin; Kim, Mi Gyeom; Lee, Jae Seong; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.113, no.9, pp.1953 - 1961, 2016-09 |
Combinatorial treatment with lithium chloride enhances recombinant antibody production in transiently transfected CHO and HEK293E cells Kim, Che Lin; Ha, Tae Kwang; Lee, Gyun Min, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.21, no.5, pp.667 - 675, 2016-09 |
Comparative Lipidomic Profiling of Two Dunaliella tertiolecta Strains with Different Growth Temperatures under Nitrate-Deficient Conditions Kim, So-Hyun; Ahn, Hye Min; Lim, Sa Rang; Hong, Seong-Joo; Cho, Byung-Kwan; Lee, Hookeun; Lee, Choul-Gyun; et al, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, v.63, no.3, pp.880 - 887, 2015-01 |
Comparison between ELISA and gel-filtration assay for the quantitation of airway mucins Shin, Chan Young; Kang, Suk-Jo; Kim, Kwang Chul; Ko, Kwang Ho, ARCHIVES OF PHARMACAL RESEARCH, v.21, no.3, pp.253 - 259, 1998-06 |
Controlling Medium Osmolality Improves the Expansion of Human Articular Chondrocytes in Serum-Free Media Koo, Jane; Kim, Kang-Il; Min, Byoung-Hyun; Lee, Gyun-Min, TISSUE ENGINEERING PART C-METHODS, v.16, no.5, pp.957 - 963, 2010-10 |
Development of a serum-free medium for in vitro expansion of human cytotoxic T lymphocytes using a statistical design![]() Jeon, Min-Kyoung; Lim, Jong-Baeck; Lee, Gyun-Min, BMC BIOTECHNOLOGY, v.10, 2010-09 |
Development of apoptosis-resistant CHO cell line expressing PyLT for the enhancement of transient antibody production Kim, Won-Hee; Kim, Min-Soo; Kim, Yeon-Gu; Lee, Gyun-Min, PROCESS BIOCHEMISTRY, v.47, no.12, pp.2557 - 2561, 2012-12 |
Differential in-gel electrophoresis (DIGE) analysis of CHO cells under hyperosmotic pressure: Osmoprotective effect of glycine betaine addition Kim, Jee Yon; Kim, Yeon-Gu; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.109, no.6, pp.1395 - 1403, 2012-06 |
Differential induction of autophagy in caspase-3/7 down-regulating and Bcl-2 overexpressing recombinant CHO cells subjected to sodium butyrate treatment Lee, Jae-Seong; Kim, Yeon-Jung; Kim, Che-Lin; Lee, Gyun-Min, JOURNAL OF BIOTECHNOLOGY, v.161, no.1, pp.34 - 41, 2012-09 |
DNA Transfection Using Linear Poly(ethylenimine) Prepared by Controlled Acid Hydrolysis of Poly(2-ethyl-2-oxazoline) Jeong, JH; Song, SH; Lim, DW; Lee, H; Park, Tae Gwan, J. CONTROLLED RELEASE, v.73, no.2-3, pp.391 - 399, 2001-06 |
Effect of Akt overexpression on programmed cell death in antibody-producing Chinese hamster ovary cells Hwang, Sun Ok; Lee, Gyun-Min, JOURNAL OF BIOTECHNOLOGY, v.139, no.1, pp.89 - 94, 2009-01 |
Effect of Bcl-x(L) Overexpression on Lactate Metabolism in Chinese Hamster Ovary Cells Producing Antibody Ha, Tae-Kwang; Jeon, Min-Kyoung; Yu, Da-Young; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.29, no.6, pp.1594 - 1598, 2013-11 |
Effect of Chemical Chaperone Addition on Production and Aggregation of Recombinant Flag-Tagged COMP-Angiopoietin 1 in Chinese Hamster Ovary Cells Hwang, Su-Jeong; Jeon, Choon-Ju; Cho, Sung-Min; Lee, Gyun-Min; Yoon, Sung-Kwan, BIOTECHNOLOGY PROGRESS, v.27, no.2, pp.587 - 591, 2011 |
Effect of Doxycycline-Regulated Calnexin and Calreticulin Expression on Specific Thrombopoietin Productivity of Recombinant Chinese Hamster Ovary Cells Chung J.Y.; Lim S.W.; Hong Y.J.; Hwang S.O.; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.85, no.5, pp.539 - 546, 2004-03 |
Effect of human leukemia inhibitory factor on in vitro development of IVF-derived bovine morulae and blastocysts Han, Yong Mahn; LEE, ES; MOGOE, T; LEE, KK; FUKUI, Y, THERIOGENOLOGY, v.44, no.4, pp.507 - 516, 1995-09 |
Effect of Mild-Thiol Reducing Agents and alpha 2,3-Sialyltransferase Expression on Secretion and Sialylation of Recombinant EPO in CHO Cells Chang, Kern Hee; Jeong, Yeon Tae; Kwak, Chan Yeong; Choi, One; Kim, Jung Hoe, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.23, no.5, pp.699 - 706, 2013-05 |
Effect of sodium butyrate on autophagy and apoptosis in Chinese hamster ovary cells Lee, Jae-Seong; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.28, no.2, pp.349 - 357, 2012-03 |
Effects of cloned gene dosage on the response of recombinant CHO cells to hyperosmotic pressure in regard to cell growth and antibody production Ryu, J.S.; Lee, M.S.; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.17, no.6, pp.993 - 999, 2001-11 |
Enhanced cell growth, production, and mAb quality produced in Chinese hamster ovary-K1 cells by supplementing polyamine in the media Kang, Da Eun; An, Yeong Bin; Kim, Yeunju; Ahn, Seawon; Kim, Young Jin; Lim, Jung Soo; Ryu, Soo Hyun; et al, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.107, no.9, pp.2855 - 2870, 2023-05 |
Enhanced Sialylation of Recombinant Erythropoietin in CHO Cells by Human Glycosyltransferase Expression Yeon Tae Jeong; One Choi; Hye Rim Lim; Young Dok Son; Hong Jin Kim; Kim, Jung Hoe, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.18, pp.1945 - 1952, 2008-12 |
ENHANCED SPECIFIC ANTIBODY PRODUCTIVITY OF HYBRIDOMAS RESULTING FROM HYPEROSMOTIC STRESS IS CELL LINE-SPECIFIC Lee, Gyun Min; Park, SY, BIOTECHNOLOGY LETTERS, v.17, no.2, pp.145 - 150, 1995-12 |
Estimation of autophagy pathway genes for autophagy induction: Overexpression of Atg9A does not induce autophagy in recombinant Chinese hamster ovary cells Lee, Jae-Seong; Lee, Gyun-Min, BIOCHEMICAL ENGINEERING JOURNAL, v.68, pp.221 - 226, 2012-10 |
Ettlia sp YC001 showing high growth rate and lipid content under high CO2 Yoo, Chan; Choi, Gang-Guk; Kim, Sun-Chang; Oh, Hee-Mock, BIORESOURCE TECHNOLOGY, v.127, pp.482 - 488, 2013-01 |
Fabrication of Adipose-Derived Mesenchymal Stem Cell Aggregates using Biodegradable Porous Microspheres for Injectable Adipose Tissue Regeneration Chung, Hyun Jung; Jung, Jin Sup; Park, Tae Gwan, JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, v.22, no.1-3, pp.107 - 122, 2011 |
Flow cytometric application of helper adenovirus (HAd) containing GFP gene flanked by two parallel loxP sites to evaluation of 293 cre-complementing cell line and monitoring of HAd in gutless Ad production Park, MT; Hwang, SJ; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.20, pp.913 - 920, 2004-05 |
Heparan sulfate proteoglycan synthesis in CHO DG44 and HEK293 cells Lee, Sojeong; Kim, Mi Gyeom; Kim, Nury; Heo, Won Do; Lee, Gyun Min, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.21, no.3, pp.439 - 445, 2016-06 |
High productivity of t-PA in CHO cells using hypoxia response element Bae, GW; Jeong, DW; Kim, HJ; Lee, Gyun-Min; Park, H; Choe, TB; Kang, S; et al, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.16, pp.695 - 703, 2006-05 |
Highly open porous biodegradable microcarriers: In vitro cultivation of chondrocytes for injectable delivery Chung, Hyun Jung; Kim, In Kyoung; Kim, Taek Gyoung; Park, Tae Gwan, TISSUE ENGINEERING, v.14, no.5, pp.607 - 615, 2008-05 |
Hyaluronic acid modified biodegradable scaffolds for cartilage tissue engineering Yoo, Hyuk Sang; Lee, Eun Ah; Yoon, Jun Jin; Park, Tae Gwan, BIOMATERIALS, v.26, no.14, pp.1925 - 1933, 2005-05 |
Hyperosmotic pressure enhances immunoglobulin transcription rates and secretion rates of KR12H-2 transfectoma Lee, MS; Lee, Gyun-Min, BIOTECHNOLOGY AND BIOENGINEERING, v.68, no.3, pp.260 - 268, 2000-05 |
Immobilization of cell adhesive RGD peptide onto the surface of highly porous biodegradable polymer scaffolds fabricated by a gas foaming/salt leaching method Yoon, JJ; Song, SH; Lee, DS; Park, TG, BIOMATERIALS, v.25, no.25, pp.5613 - 5620, 2004-11 |
INDIRECT ESTIMATION OF CELL MASS AND SUBSTRATE CONCENTRATION USING A COMPUTER-COUPLED MASS-SPECTROMETER Nam, SW; Kim, Jung-Hoe, JOURNAL OF FERMENTATION AND BIOENGINEERING, v.77, no.3, pp.332 - 334, 1994 |
Influence of co-down-regulation of caspase-3 and caspase-7 by siRNAs on sodium butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin Sung, Yun-Hee; Lee, Jae-Seong; Park, Soon-Hye; Koo, Jane; Lee, Gyun-Min, METABOLIC ENGINEERING, v.9, pp.452 - 464, 2007-09 |
Inhibition of poly-LacNAc biosynthesis with release of CMP-Neu5Ac feedback inhibition increases the sialylation of recombinant EPO produced in CHO cells![]() Lee, Chung Geun; Oh, Myung Jin; Park, Seung-Yeol; An, Hyun Joo; Kim, Jung Hoe, SCIENTIFIC REPORTS, v.8, 2018-05 |
Intracellular responses of antibody-producing H69K-NGD transfectoma subjected to hyperosmotic pressure Bae, SW; Lee, Gyun-Min, JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.15, pp.579 - 586, 2005-06 |
Limitations to the comparative proteomic analysis of thrombopoietin producing Chinese hamster ovary cells treated with sodium butyrate Baik, Jong Youn; Joo, Eun Jin; Kim, Young Hwan; Lee, Gyun-Min, JOURNAL OF BIOTECHNOLOGY, v.133, no.4, pp.461 - 468, 2008-02 |
Long-term, feeder-free maintenance of human embryonic stem cells by mussel-inspired adhesive heparin and collagen type I Lee, Mihyun; Kim, Youngjin; Ryu, Ji Hyun; Kim, Kyuri; Han, Yong-Mahn; Lee, Haeshin, ACTA BIOMATERIALIA, v.32, pp.138 - 148, 2016-03 |
Metabolic engineering of Pichia pastoris for production of hyaluronic acid with high molecular weight Jeong, Euijoon; Shim, Woo Yong; Kim, Jung Hoe, JOURNAL OF BIOTECHNOLOGY, v.185, pp.28 - 36, 2014-09 |
Microfluidic-based observation of local bacterial density under antimicrobial concentration gradient for rapid antibiotic susceptibility testing Kim, Seunggyu; Lee, Seokhun; Kim, Ju-Kang; Chung, Hyun Jung; Jeon, Jessie Sungyun, BIOMICROFLUIDICS, v.13, no.1, pp.014108, 2019-01 |
Monitoring of autophagy in Chinese hamster ovary cells using flow cytometry Lee, Jae-Seong; Lee, Gyun-Min, METHODS, v.56, no.3, pp.375 - 382, 2012-03 |
OBSERVATIONS CONSISTENT WITH AUTOCRINE STIMULATION OF HYBRIDOMA CELL-GROWTH AND IMPLICATIONS FOR LARGE-SCALE ANTIBODY-PRODUCTION Lee, Gyun Min; Kaminski, MS; Palsson, BO, BIOTECHNOLOGY LETTERS, v.14, no.4, pp.257 - 262, 1992-12 |
Penetration and efficacy of VEGF siRNA using polyelectrolyte complex micelles in a human solid tumor model in-vitro Al-Abd, Ahmed M.; Lee, Soo-Hyeon; Kim, Sun-Hwa; Cha, Jung-Ho; Park, Tae-Gwan; Lee, Seung-Jin; Kuh, Hyo-Jeong, JOURNAL OF CONTROLLED RELEASE, v.137, no.2, pp.130 - 135, 2009-07 |
Prostacyclin stimulates embryonic development via regulation of the cAMP response element-binding protein-cyclo-oxygenase-2 signalling pathway in cattle Song, Bong-Seok; Kim, Ji-Su; Kim, Cheol-Hee; Han, Yong Mahn; Lee, Dong-Seok; Lee, Kyung-Kwang; Koo, Deog-Bon, REPRODUCTION FERTILITY AND DEVELOPMENT, v.21, no.3, pp.400 - 407, 2009 |
Protein Binder for Affinity Purification of Human Immunoglobulin Antibodies Heu, Woosung; Choi, Jung-Min; Lee, Joong-Jae; Jeong, Sukyo; Kim, Hak-Sung, ANALYTICAL CHEMISTRY, v.86, no.12, pp.6019 - 6025, 2014-06 |
Proteome analysis of antibody-expressing CHO cells in response to hyperosmotic pressure Lee, MS; Kim, KW; Kim, YH; Lee, Gyun-Min, BIOTECHNOLOGY PROGRESS, v.19, no.6, pp.1734 - 1741, 2003-11 |
Reduction of ammonia and lactate through the coupling of glutamine synthetase selection and downregulation of lactate dehydrogenase-A in CHO cells Noh, Soo Min; Park, Jin-Hyoung; Lim, Myung Sin; Kim, Jong Won; Lee, Gyun Min, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.101, no.3, pp.1035 - 1045, 2017-02 |
Role of cytosolic malate dehydrogenase in oocyte maturation and embryo development Yoon, Se-Jin; Koo, Deog-Bon; Park, Jung Sun; Choi, Kyung-Hee; Han, Yong Mahn; Lee, Kyung-Ah, FERTILITY AND STERILITY, v.86, no.4 Suppl, pp.1129 - 1136, 2006-10 |
SPATIAL-DISTRIBUTION OF MAMMALIAN-CELLS GROWN ON MACROPOROUS MICROCARRIERS WITH IMPROVED ATTACHMENT KINETICS LIM, HS; HAN, BK; Kim, Jung-Hoe; PESHWA, MV; HU, WS, BIOTECHNOLOGY PROGRESS, v.8, no.6, pp.486 - 493, 1992-11 |
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