Browse "Graduate School of Medical Science & Engineering(의과학대학원)" by Subject MECHANISMS
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| A cell atlas of human thymic development defines T cell repertoire formation Park, Jong-Eun; Botting, Rachel A.; Conde, Cecilia Dominguez; Popescu, Dorin-Mirel; Lavaert, Marieke; Kunz, Daniel J.; Goh, Issac; et al, SCIENCE, v.367, no.6480, pp.868 - +, 2020-02 |
| A unique population of neutrophils generated by air pollutant-induced lung damage exacerbates airway inflammation Shin, Jae Woo; Kim, Jihyun; Ham, Seokjin; Choi, Sun Mi; Lee, Chang-Hoon; Lee, Jung Chan; Kim, Ji Hyung; et al, JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, v.149, no.4, pp.1253 - +, 2022-04 |
| Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis Jeong, Won-il; Park, Ogyi; Gao, Bin, GASTROENTEROLOGY, v.134, no.1, pp.248 - 258, 2008-01 |
| Acquired Resistance to Third-Generation EGFR Tyrosine Kinase Inhibitors in Patients With De Novo EGFR(T790M)-Mutant NSCLC Park, Ha-Ram; Kim, Tae Min; Lee, Yusoo; Kim, Soyeon; Park, Seongyeol; Ju, Young Seok; Kim, Miso; et al, JOURNAL OF THORACIC ONCOLOGY, v.16, no.11, pp.1859 - 1871, 2021-11 |
| Activation of PPAR gamma induces profound multilocularization of adipocytes in adult mouse white adipose tissues Koh, Young-Jun; Park, Byung-Hyun; Park, Ji-Hyun; Han, Jin-Ah; Lee, In-Kyu; Park, Jin-Woo; Koh, Gou-Young, EXPERIMENTAL AND MOLECULAR MEDICINE, v.41, no.12, pp.880 - 895, 2009-12 |
| Activity of angiotensin peptides in clitoral cavernosum of alloxan induced diabetic rabbit Park, JK; Lee, SO; Cui, WS; Kim, SZ; Koh, Gou Young; Cho, KW, EUROPEAN UROLOGY, v.48, no.6, pp.1042 - 1050, 2005-12 |
| Adaptive Natural Killer Cells Facilitate Effector Functions of Daratumumab in Multiple Myeloma Cho, Hyunsoo; Kim, Kyung Hwan; Lee, Hoyoung; Kim, Chang Gon; Chung, Haerim; Choi, Yoon Seok; Park, Su-Hyung; et al, CLINICAL CANCER RESEARCH, v.27, no.10, pp.2947 - 2958, 2021-05 |
| Aggravation of post-ischemic liver injury by overexpression of insulin-like growth factor binding protein 3 Zhou, Lu; Koh, Hyoung-Won; Bae, Ui-Jin; Park, Byung-Hyun, SCIENTIFIC REPORTS, v.5, 2015-06 |
| Alleviating psoriatic skin inflammation through augmentation of Treg cells via CTLA-4 signaling peptide Lee, Woo-Sung; Nam, Kyung-Ho; Kim, Jong Hoon; Kim, Won-Ju; Kim, Jeong Eun; Shin, Eui-Cheol; Kim, Gil-Ran; et al, FRONTIERS IN IMMUNOLOGY, v.14, 2023-09 |
| An Indole Derivative Protects Against Acetaminophen-Induced Liver Injury by Directly Binding to N-Acetyl-p-Benzoquinone Imine in Mice Park, Ji-Hoon; Seo, Kang-Sik; Tadi, Surendar; Ahn, Bong-Hyun; Lee, Jung-Uee; Heo, Jun-Young; Han, Jeongsu; et al, ANTIOXIDANTS & REDOX SIGNALING, v.18, no.14, pp.1713 - 1722, 2013-05 |
| Analysis of low-level somatic mosaicism reveals stage and tissue-specific mutational features in human development Kim, Ja Hye; Hwang, Shinwon; Son, Hyeonju; Kim, Dongsun; Kim, Il Bin; Kim, Myeong-Heui; Sim, Nam Suk; et al, PLOS GENETICS, v.18, no.9, 2022-09 |
| Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion. Kim, Injune; Kim HG; Moon SO; Chae SW; So JN; Koh KN; Ahn BC; et al, CIRCULATION RESEARCH, v.86, no.9, pp.952 - 959, 2000-05 |
| Angiopoietin-1 prevents hypertension and target organ damage through its interaction with endothelial Tie2 receptor Lee, Jung-Sun; Song, Sun-Hwa; Kim, Jeong-Min; Shin, In-Soon; Kim, Koung Li; Suh, Yeon-Lim; Kim, Hak-Zoo; et al, CARDIOVASCULAR RESEARCH, v.78, no.3, pp.572 - 580, 2008-11 |
| Angiopoietin-2 at high concentration can enhance endothelial cell survival through the phosphatidylinositol 3-kinase/Akt signal transduction pathway. Kim, Injune; Kim JH; Moon SO; Kwak HJ; Kim NG; Koh, Gou Young, ONCOGENE, v.19, no.39, pp.4549 - 4552, 2000-09 |
| APP-C31: An Intracellular Promoter of Both Metal-Free and Metal-Bound Amyloid-β<sub>40</sub> Aggregation and Toxicity in Alzheimer's Disease Nam, Eunju; Lin, Yuxi; Park, Jiyong; Do, Hyunsu; Han, Jiyeon; Jeong, Bohyeon; Park, Subin; et al, ADVANCED SCIENCE, v.11, no.4, 2024-01 |
| Bilirubin nanoparticles ameliorate allergic lung inflammation in a mouse model of asthma Kim, Dong Eon; Lee, Yonghyun; Kim, Mingyo; Lee, Soyoung; Jon, Sangyong; Lee, Seung-Hyo, BIOMATERIALS, v.140, pp.37 - 44, 2017-09 |
| BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors Koh, Hyun Yong; Kim, Se Hoon; Jang, Jaeson; Kim, Hyungguk; Han, Sungwook; Lim, Jae Seok; Son, Geurim; et al, NATURE MEDICINE, v.24, no.11, pp.1662 - 1668, 2018-11 |
| Brain somatic mutations as RNA therapeutic targets in neurological disorders Lee, Sungyul; Lee, Jeong Ho, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, v.1514, no.1, pp.11 - 20, 2022-08 |
| Cannabidiol Inhibits IgE-Mediated Mast Cell Degranulation and Anaphylaxis in Mice Yang, Xiaohui; Lee, Dohyeon; Kim, Hyun-Woo; Park, Byung-Hyun; Lim, Changjin; Bae, Eun Ju, MOLECULAR NUTRITION FOOD RESEARCH, v.68, no.3, 2024-02 |
Cerebral amyloid angiopathy aggravates perivascular clearance impairment in an Alzheimer's disease mouse model Kim, Shin Heun; Ahn, Ji Hoon; Yang, Hyunwoo; Lee, Peter; Koh, Gou Young; Jeong, Yong, ACTA NEUROPATHOLOGICA COMMUNICATIONS, v.8, no.1, pp.181, 2020-11 |
| Characterization of CD8(+)CD57(+) T cells in patients with acute myocardial infarction Yu, Hee Tae; Youn, Jong-Chan; Lee, Jino; Park, Seunghyun; Chi, Ho-Seok; Lee, Jungsul; Choi, Chulhee; et al, CELLULAR & MOLECULAR IMMUNOLOGY, v.12, no.4, pp.466 - 473, 2015-07 |
| Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis Petljak, Mia; Alexandrov, Ludmil B.; Brammeld, Jonathan S.; Price, Stacey; Wedge, David C.; Grossmann, Sebastian; Dawson, Kevin J.; et al, CELL, v.176, no.6, pp.1282 - 1294, 2019-03 |
| Clonal History and Genetic Predictors of Transformation Into Small-Cell Carcinomas From Lung Adenocarcinomas Lee, June Koo; Lee, Junehawk; Kim, Sehui; Kim, Soyeon; Youk, Jeonghwan; Park, Seongyeol; An, Yohan; et al, JOURNAL OF CLINICAL ONCOLOGY, v.35, no.26, pp.3065 - +, 2017-09 |
| Coiled-coil structure-dependent interactions between polyQ proteins and Foxo lead to dendrite pathology and behavioral defects Kwon, Min Jee; Han, Myeong Hoon; Bagley, Joshua A.; Hyeon, Do Young; Ko, Byung Su; Lee, Yun Mi; Cha, In Jun; et al, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.115, no.45, pp.E10748 - E10757, 2018-11 |
| Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing Cortes-Ciriano, Isidro; Lee, Jake June-Koo; Xi, Ruibin; Jain, Dhawal; Jung, Youngsook L.; Yang, Lixing; Gordenin, Dmitry; et al, NATURE GENETICS, v.52, no.3, pp.331, 2020-03 |
| Corticosteroids reduce pathologic interferon responses by downregulating STAT1 in patients with high-risk COVID-19 Jeong, Hyun-Woo; Lee, Jeong Seok; Ko, Jae-Hoon; Hong, Seunghee; Oh, Sang Taek; Choi, Seongkyun; Peck, Kyong Ran; et al, EXPERIMENTAL AND MOLECULAR MEDICINE, v.55, no.3, pp.653 - 664, 2023-03 |
| Current Understanding of the Innate Control of Toll-like Receptors in Response to SARS-CoV-2 Infection Jung, Hi Eun; Lee, Heung Kyu, VIRUSES-BASEL, v.13, no.11, 2021-11 |
| Cytotoxic effects of the conjugated linoleic acid isomers t10c12, c9t11-CLA and mixed form on rat hepatic stellate cells and CCl4-induced hepatic fibrosis Yun, HS; Do, SH; Jeong, Won-il; Yang, HH; Yuan, DW; Hong, IH; Lee, HR; et al, JOURNAL OF NUTRITIONAL BIOCHEMISTRY, v.19, no.3, pp.175 - 183, 2008-03 |
| Dicer recognizes the 5 ' end of RNA for efficient and accurate processing Park, Jong-Eun; Heo, Inha; Tian, Yuan; Simanshu, Dhirendra K.; Chang, Hyeshik; Jee, David; Patel, Dinshaw J.; et al, NATURE, v.475, no.7355, pp.201 - U107, 2011-07 |
| Differences in the amount of lipolysis induced by atrial natriuretic peptide in small and large adipocytes Yu, Jiahua; Yu, Hee-Chul; Kim, Kyung-Ah; Kwon, Kang-Beom; Park, Jin-Woo; Kim, Sung-Zoo; Kim, Suhn Hee; et al, JOURNAL OF PEPTIDE SCIENCE, v.14, no.8, pp.972 - 977, 2008-08 |
| Disruption of CR6-interacting factor-1 (CRIF1) in mouse islet beta cells leads to mitochondrial diabetes with progressive beta cell failure Kim, Yong Kyung; Joung, Kyong Hye; Ryu, Min Jeong; Kim, Soung Jung; Kim, Hyeongseok; Chung, Hyo Kyun; Lee, Min Hee; et al, DIABETOLOGIA, v.58, no.4, pp.771 - 780, 2015-04 |
| Dissecting single-cell genomes through the clonal organoid technique Youk, Jeonghwan; Kwon, Hyun Woo; Kim, Ryul; Ju, Young Seok, EXPERIMENTAL AND MOLECULAR MEDICINE, v.53, pp.1503 - 1511, 2021-10 |
| Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi Hong, Seon Pyo; Yang, Myung Jin; Cho, Hyunsoo; Park, Intae; Bae, Hosung; Choe, Kibaek; Suh, Sang Heon; et al, NATURE COMMUNICATIONS, v.11, no.1, 2020-08 |
| Dysregulation of Parkin-mediated mitophagy in thyroid Hurthle cell tumors Lee, Junguee; Ham, Sujin; Lee, Min Hee; Kim, Soung Jung; Park, Ji Hoon; Lee, Seong Eun; Chang, Joon Young; et al, CARCINOGENESIS, v.36, no.11, pp.1407 - 1418, 2015-11 |
| Enhanced thrombospondin-1 causes dysfunction of vascular endothelial cells derived from Fabry disease-induced pluripotent stem cells Do, Hyo-Sang; Park, Sang-Wook; Im, Ilkyun; Seo, Donghyuk; Yoo, Han-Wook; Go, Heounjeong; Kim, Yoo Hyung; et al, EBIOMEDICINE, v.52, pp.102633, 2020-02 |
| Exogenous Hydrogen Peroxide Induces Lipid Raft-Mediated STAT-6 Activation in T Cells Kim, Hee Ja; Lim, Jiwoo; Jang, Young-Soon; Shin, Eui-Cheol; Kim, Hyung-Ran; Seoh, Ju-Young; Lee, Ji Soo; et al, CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, v.42, no.6, pp.2467 - 2480, 2017 |
| Expansion of CD45RA(-)FOXP3(++) regulatory T cells is associated with immune tolerance in patients with combined kidney and bone marrow transplantation Kwon, Yeongbeen; Lee, Kyo Won; Kim, You Min; Park, Hyojun; Jung, Min Kyung; Choi, Young Joon; Son, Jin Kyung; et al, CLINICAL & TRANSLATIONAL IMMUNOLOGY, v.10, no.8, 2021 |
| Expression of fas ligand in human hepatoma cell lines: Role of hepatitis-B virus X (HBx) in induction of Fas ligand Shin, Eui-Cheol; Shin, JS; Park, JH; Kim, H; Kim, SJ, INTERNATIONAL JOURNAL OF CANCER, v.82, no.4, pp.587 - 591, 1999-08 |
| Fenofibrate Differentially Regulates Plasminogen Activator Inhibitor-1 Gene Expression via Adenosine Monophosphate-Activated Protein Kinase-Dependent Induction of Orphan Nuclear Receptor Small Heterodimer Partner Chanda, Dipanjan; Lee, Chul Ho; Kim, Yong-Hoon; Noh, Jung-Ran; Kim, Don-Kyu; Park, Ji-Hoon; Hwang, Jung Hwan; et al, HEPATOLOGY, v.50, no.3, pp.880 - 892, 2009-09 |
| Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells Ju, Young Seok; Tubio, Jose M. C.; Mifsud, William; Fu, Bei Yuan; Davies, Helen R.; Ramakrishna, Manasa; Li, Yi Long; et al, GENOME RESEARCH, v.25, no.6, pp.814 - 824, 2015-06 |
| Functional Role of Serotonin in Insulin Secretion in a Diet-Induced Insulin-Resistant State Kim, Kyu Ho; Oh, Chang Myung; Ohara-Imaizumi, Mica; Park, Sangkyu; Namkung, Jun; Yadav, Vijay K.; Tamarina, Natalia A.; et al, ENDOCRINOLOGY, v.156, no.2, pp.444 - 452, 2015-02 |
| Gatekeeping role of Nf2/Merlin in vascular tip EC induction through suppression of VEGFR2 internalization Bae, Jung Hyun; Yang, Myung Jin; Jeong, Seung-Hwan; Kim, JungMo; Hong, Seon Pyo; Kim, Jin Woo; Kim, Yoo Hyung; et al, SCIENCE ADVANCES, v.8, no.23, 2022-06 |
| Ginsenoside F2 attenuates chronic-binge ethanol-induced liver injury by increasing regulatory T cells and decreasing Th17 cells Kim, Myung-Ho; Kim, Hee-Hoon; Jeong, Jong-Min; Shim, Young-Ri; Lee, Jun-Hee; Kim, Ye Eun; Ryu, Tom; et al, JOURNAL OF GINSENG RESEARCH, v.44, no.6, pp.815 - 822, 2020-11 |
| Glucocorticoid Suppresses Connexin 43 Expression by Inhibiting the Akt/mTOR Signaling Pathway in Osteoblasts Shen, Chen; Kim, Mi Ran; Noh, Jeong Mi; Kim, Su Jin; Ka, Sun-O; Kim, Ji Hye; Park, Byung-Hyun; et al, CALCIFIED TISSUE INTERNATIONAL, v.99, no.1, pp.88 - 97, 2016-07 |
| Hydrogen peroxide produced by anglopoietin-1 mediates angiogenesis-1 Kim, YM; Kim, KE; Koh, Gou Young; Ho, YS; Lee, K, CANCER RESEARCH, v.66, no.12, pp.6167 - 6174, 2006-06 |
| Immaturity of immune cells around the dural venous sinuses contributes to viral meningoencephalitis in neonates Kim, Young-Chan; Ahn, Ji Hoon; Jin, Hokyung; Yang, Myung Jin; Hong, Seon Pyo; Yoon, Jin-Hui; Kim, Sang-Hoon; et al, SCIENCE IMMUNOLOGY, v.8, no.88, 2023-10 |
| Immunosenescent CD8(+) T Cells and C-X-C Chemokine Receptor Type 3 Chemokines Are Increased in Human Hypertension Youn, Jong-Chan; Yu, Hee-Tae; Lim, Beom-Jin; Koh, Myoung-Ju; Lee, Jin-O; Chang, Dong-Yeop; Choi, Yoon-Seok; et al, HYPERTENSION, v.62, no.1, pp.126 - 133, 2013-07 |
| Increase of V delta 2(+) T Cells That Robustly Produce IL-17A in Advanced Abdominal Aortic Aneurysm Tissues Seo, In-Ho; Lee, Seung-Jun; Noh, Tae Wook; Kim, Jung-Hwan; Joo, Hyun-Chel; Shin, Eui-Cheol; Park, Su-Hyung; et al, IMMUNE NETWORK, v.21, no.2, 2021-04 |
| Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration Choi, Jinwook; Park, Jong-Eun; Tsagkogeorga, Georgia; Yanagita, Motoko; Koo, Bon-Kyoung; Han, Namshik; Lee, Joo-Hyeon, CELL STEM CELL, v.27, no.3, pp.366 - +, 2020-09 |
| Interleukin-17A negatively regulates lymphangiogenesis in T helper 17 cell-mediated inflammation Park, H. J.; Yuk, C. M.; Shin, K.; Lee, Seung-Hyo, MUCOSAL IMMUNOLOGY, v.11, no.3, pp.590 - 600, 2018-05 |
| Intracellular mitochondrial DNA transfers to the nucleus in human cancer cells Ju, Youngseok, CURRENT OPINION IN GENETICS & DEVELOPMENT, v.38, pp.23 - 30, 2016-06 |
| KIF3A binds to beta-arrestin for suppressing Wnt/beta-catenin signalling independently of primary cilia in lung cancer Kim, Min-Suh; Suh, Young-Ah; Oh, Ju-Hee; Lee, Bo Ra; Kim, Joon; Jang, Se Jin, SCIENTIFIC REPORTS, v.6, 2016-09 |
| Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice Oh, Hyoseon; Lee, Suho; Oh, Yusang; Kim, Seongbin; Kim, Young Seo; Yang, Yeji; Choi, Woochul; et al, NATURE COMMUNICATIONS, v.14, no.1, 2023-06 |
| Lipopolysaccharide activates matrix metalloproteinase-2 in endothelial cells through an NF-kappa B-dependent pathway Kim, HG; Koh, Gou Young, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, v.269, no.2, pp.401 - 405, 2000-03 |
| Loss of Katnal2 leads to ependymal ciliary hyperfunction and autism-related phenotypes in mice Kang, Ryeonghwa; Kim, Kyungdeok; Jung, Yewon; Choi, Sang-Han; Lee, Chanhee; Im, Geun Ho; Shin, Miram; et al, PLOS BIOLOGY, v.22, no.5, 2024-05 |
| Metabolic improvement and liver regeneration by inhibiting CXXC5 function for non-alcoholic steatohepatitis treatment Seo, Seol Hwa; Kim, Eunhwan; Yoon, Minguen; Lee, Soung-Hoon; Park, Byung-Hyun; Choi, Kang-Yell, EXPERIMENTAL AND MOLECULAR MEDICINE, v.54, no.9, pp.1511 - 1523, 2022-09 |
| Metformin decreases high-fat diet-induced renal injury by regulating the expression of adipokines and the renal AMP-activated protein kinase/acetyl-CoA carboxylase pathway in mice Kim, Dal; Lee, Jung Eun; Jung, Yu Jin; Lee, Ae Sin; Lee, Sik; Park, Sung Kwang; Kim, Suhn Hee; et al, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, v.32, no.6, pp.1293 - 1302, 2013-12 |
| Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes Valente, Enza Maria; Logan, Clare V.; Mougou-Zerelli, Soumaya; Lee, Jeong Ho; Silhavy, Jennifer L.; Brancati, Francesco; Iannicelli, Miriam; et al, NATURE GENETICS, v.42, no.7, pp.619 - 625, 2010-07 |
| Myeloid deletion of SIRT1 suppresses collagen-induced arthritis in mice by modulating dendritic cell maturation Woo, Seong Ji; Lee, Sang-Myeong; Lim, Hye Song; Hah, Young-Sool; Jung, In Duk; Park, Yeong-Min; Kim, Hyun-Ok; et al, EXPERIMENTAL AND MOLECULAR MEDICINE, v.48, pp.1 - 9, 2016-03 |
| Nasopharyngeal lymphatic plexus is a hub for cerebrospinal fluid drainage Yoon, Jin-Hui; Jin, Hokyung; Kim, Hae Jin; Hong, Seon Pyo; Yang, Myung Jin; Ahn, Ji Hoon; Kim, Young-chan; et al, NATURE, v.625, no.7996, 2024-01 |
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