A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-beta implicated in Alzheimer's disease
Alzheimer's disease (AD) is a complex, multifactorial, neurodegenerative disease that poses tremendous difficulties in pinpointing its precise etiology. A toolkit, which specifically targets and modulates suggested key players, may elucidate their roles in disease onset and progression. We report high-resolution insights on the activity of a small molecule (L2-NO) which exhibits reactivity toward Cu(II)-amyloid-beta (A beta) over Zn(II)-A beta.
- Publisher
- ROYAL SOC CHEMISTRY
- Issue Date
- 2014-05
- Language
- English
- Article Type
- Article
- Citation
CHEMICAL COMMUNICATIONS, v.50, no.40, pp.5301 - 5303
- ISSN
- 1359-7345
- Appears in Collection
- CH-Journal Papers(저널논문)
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