DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jung, Young-Kyun | ko |
dc.contributor.author | Jeon, Chan-Il | ko |
dc.contributor.author | Kim, Ju-In | ko |
dc.contributor.author | Jeong, Ha-Woong | ko |
dc.contributor.author | Jun, Suck-Joon | ko |
dc.contributor.author | Ha, Bae-Yeun | ko |
dc.date.accessioned | 2013-03-09T17:25:16Z | - |
dc.date.available | 2013-03-09T17:25:16Z | - |
dc.date.created | 2012-04-03 | - |
dc.date.created | 2012-04-03 | - |
dc.date.issued | 2012-01 | - |
dc.identifier.citation | SOFT MATTER, v.8, no.7, pp.2095 - 2102 | - |
dc.identifier.issn | 1744-683X | - |
dc.identifier.uri | http://hdl.handle.net/10203/96987 | - |
dc.description.abstract | Chromosomes in living cells are strongly confined but show a high level of spatial organization. Similarly, confined polymers display intriguing organizational and segregational properties. Here, we discuss how ring topology influences self-avoiding polymers confined in a cylindrical space, i.e. individual polymers as well as the way they interact. Our molecular dynamics simulations suggest that a ring polymer can be viewed as a "parallel connection'' of two linear subchains, each trapped in a narrower imaginary tube. As a consequence, ring topology "stiffens'' individual chains about fivefold and enhances their segregation appreciably, as if it induces extra linear ordering. Using a "renormalized'' Flory approach, we show how ring topology influences individual chains in the long chain limit. Our polymer model quantitatively explains the long-standing observations of chromosome organization and segregation in E. coli. | - |
dc.language | English | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.subject | ESCHERICHIA-COLI CHROMOSOME | - |
dc.subject | SEPARATE CELL HALVES | - |
dc.subject | SEGREGATION | - |
dc.subject | DYNAMICS | - |
dc.subject | DNA | - |
dc.subject | ENTROPY | - |
dc.subject | ARMS | - |
dc.title | Ring polymers as model bacterial chromosomes: confinement, chain topology, single chain statistics, and how they interact | - |
dc.type | Article | - |
dc.identifier.wosid | 000299477300004 | - |
dc.identifier.scopusid | 2-s2.0-84863012682 | - |
dc.type.rims | ART | - |
dc.citation.volume | 8 | - |
dc.citation.issue | 7 | - |
dc.citation.beginningpage | 2095 | - |
dc.citation.endingpage | 2102 | - |
dc.citation.publicationname | SOFT MATTER | - |
dc.identifier.doi | 10.1039/c1sm05706e | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.contributor.localauthor | Jeong, Ha-Woong | - |
dc.contributor.nonIdAuthor | Jung, Young-Kyun | - |
dc.contributor.nonIdAuthor | Jun, Suck-Joon | - |
dc.contributor.nonIdAuthor | Ha, Bae-Yeun | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI CHROMOSOME | - |
dc.subject.keywordPlus | SEPARATE CELL HALVES | - |
dc.subject.keywordPlus | SEGREGATION | - |
dc.subject.keywordPlus | DYNAMICS | - |
dc.subject.keywordPlus | DNA | - |
dc.subject.keywordPlus | ENTROPY | - |
dc.subject.keywordPlus | ARMS | - |
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