DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yang, Hee-Man | ko |
dc.contributor.author | Lee, Hyun-Jin | ko |
dc.contributor.author | Jang, Kwang-Suk | ko |
dc.contributor.author | Park, Chan-Woo | ko |
dc.contributor.author | Yang, Hee-Won | ko |
dc.contributor.author | Heo, Won-Do | ko |
dc.contributor.author | Kim, Jong-Duk | ko |
dc.date.accessioned | 2013-03-11T11:50:24Z | - |
dc.date.available | 2013-03-11T11:50:24Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | JOURNAL OF MATERIALS CHEMISTRY, v.19, no.26, pp.4566 - 4574 | - |
dc.identifier.issn | 0959-9428 | - |
dc.identifier.uri | http://hdl.handle.net/10203/99237 | - |
dc.description.abstract | A biocompatible and water-soluble poly( amino acid) derivative, with a hydrophilic backbone and side chains facilitating linkage to the surfaces of nanoparticles was used to coat hydrophobic Fe(3)O(4) nanoparticles. Such nanoparticles, (4-11 nm), were coated by coordinate bonding and hydrophobic interactions with a hydrophilic poly( amino acid) derivative, poly(2-hydroxyethyl aspartamide). This is a new method for the transfer of hydrophobic nanoparticles from organic solvents into water. The biocompatible poly(amino acid)-coated Fe(3)O(4) nanoparticles were smaller than 30 nm in aqueous solutions, extremely stable, and maintained their stability even after several lyophilizations. The poly(amino acid)-coated nanoparticles showed no cytotoxicity, good saturation magnetization, and high T(2) relaxivity coefficients (r(2) values). The poly( amino acid)-coated Fe(3)O(4) nanoparticles demonstrate strong potential in bioapplications such as magnetic resonance imaging (MRI). | - |
dc.language | English | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Poly(amino acid)-coated iron oxide nanoparticles as ultra-small magnetic resonance probes | - |
dc.type | Article | - |
dc.identifier.wosid | 000267439500016 | - |
dc.identifier.scopusid | 2-s2.0-67649678494 | - |
dc.type.rims | ART | - |
dc.citation.volume | 19 | - |
dc.citation.issue | 26 | - |
dc.citation.beginningpage | 4566 | - |
dc.citation.endingpage | 4574 | - |
dc.citation.publicationname | JOURNAL OF MATERIALS CHEMISTRY | - |
dc.identifier.doi | 10.1039/b820139k | - |
dc.contributor.localauthor | Heo, Won-Do | - |
dc.contributor.localauthor | Kim, Jong-Duk | - |
dc.contributor.nonIdAuthor | Yang, Hee-Won | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | WATER-SOLUBLE NANOCRYSTALS | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | SUPERPARAMAGNETIC NANOPARTICLES | - |
dc.subject.keywordPlus | CONTRAST AGENTS | - |
dc.subject.keywordPlus | BIOMEDICAL APPLICATIONS | - |
dc.subject.keywordPlus | AMPHIPHILIC POLYMER | - |
dc.subject.keywordPlus | BLOCK-COPOLYMERS | - |
dc.subject.keywordPlus | AQUEOUS-SOLUTION | - |
dc.subject.keywordPlus | DELIVERY-SYSTEM | - |
dc.subject.keywordPlus | CANCER | - |
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