Two-photon microscopy by wavelength-swept pulses delivered through single-mode fiber

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Nonlinear microscopy through flexible fiber-optic catheters has potential in clinical diagnostic applications. Here, we demonstrate a new approach based on wavelength-swept narrowband pulses that permits simple fiber-optic delivery without need of the dispersion management and allows nonmechanical beam scanning. Using 0.86 ps pulses rapidly tuned from 789 nm to 822 nm at a sweep rate of 200 Hz, we demonstrate two-photon fluorescence and second-harmonic generation imaging through a 5-m-long standard single-mode fiber. (C) 2010 Optical Society of America
Publisher
OPTICAL SOC AMER
Issue Date
2010-01
Language
English
Article Type
Article
Keywords

ENCODED CONFOCAL MICROSCOPY; OPTICAL MICROSCOPY; IN-VIVO; FLUORESCENCE; LASER

Citation

OPTICS LETTERS, v.35, no.2, pp.181 - 183

ISSN
0146-9592
DOI
10.1364/OL.35.000181
URI
http://hdl.handle.net/10203/96775
Appears in Collection
NT-Journal Papers(저널논문)
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