Electrochemical detection of DNA mutations on a PNA-modified electrode utilizing a single-stranded DNA specific endonuclease
Utilizing a peptide nucleic acid (PNA)-modified electrode and a single-stranded DNA specific endonuclease, a novel electrochemical method to identify DNA mutations has been developed and represents a totally new strategy for the electrochemical diagnosis of human genetic mutations.
- Publisher
- ROYAL SOC CHEMISTRY
- Issue Date
- 2011-05
- Language
- English
- Article Type
- Article
- Keywords
ENZYME MISMATCH CLEAVAGE; SNPS DETECTION; NUCLEASE
- Citation
CHEMICAL COMMUNICATIONS, v.47, no.23, pp.6611 - 6613
- ISSN
- 1359-7345
- Appears in Collection
- CBE-Journal Papers(저널논문)
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