DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park J.-W. | ko |
dc.contributor.author | Kim Y.-H. | ko |
dc.contributor.author | Jang S.H. | ko |
dc.contributor.author | Chang W.H. | ko |
dc.contributor.author | Park C.-H. | ko |
dc.contributor.author | Kim S.T. | ko |
dc.date.accessioned | 2013-03-09T00:26:12Z | - |
dc.date.available | 2013-03-09T00:26:12Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | NEUROREHABILITATION, v.26, no.2, pp.95 - 103 | - |
dc.identifier.issn | 1053-8135 | - |
dc.identifier.uri | http://hdl.handle.net/10203/94801 | - |
dc.description.abstract | Background: Failure of early motor learning due to damage in any brain area involved in this process may interfere with successful rehabilitation of such patients. Objective: We investigated the changes in activation of the motor network during sequential finger motor learning to delineate the characteristics of the cortico-subcortical network during motor skill learning. Methods: Twenty healthy, right-handed volunteers participated. Subjects were instructed to perform eight blocks of a sequential finger motor task while functional MRI (fMRI) was performed. Results: The participants had an improvement in performance over time from block 1 to block 4, indicating that successful learning had occurred, followed by a plateau from block 5 to the last block. On fMRI, activities of the contralateral primary sensorimotor cortex, the premotor cortex, the supplementary motor area, and the posterior parietal cortex gradually increased from block 1 to block 4 and then decreased from block 5 to the last. In contrast, activity of the ipsilateral cerebellum showed a linear increase spanning the last block with peak activation. The thalamus and basal ganglia showed unilateral or bilateral activities at the unique stage of motor learning. Conclusions: These findings delineated the characteristic plastic changes and different roles of the cortico-subcortical network during the early phase of motor learning and automatization. | - |
dc.language | English | - |
dc.publisher | IOS PRESS | - |
dc.subject | POSITRON-EMISSION-TOMOGRAPHY | - |
dc.subject | TRANSCRANIAL MAGNETIC STIMULATION | - |
dc.subject | BRAIN ACTIVATION | - |
dc.subject | VISUOMOTOR SEQUENCE | - |
dc.subject | FUNCTIONAL-ANATOMY | - |
dc.subject | SKILL ACQUISITION | - |
dc.subject | PREMOTOR CORTEX | - |
dc.subject | FRONTAL LOBES | - |
dc.subject | CEREBELLUM | - |
dc.subject | MOVEMENT | - |
dc.title | Dynamic changes in the cortico-subcortical network during early motor learning | - |
dc.type | Article | - |
dc.identifier.wosid | 000275654900001 | - |
dc.identifier.scopusid | 2-s2.0-77950204182 | - |
dc.type.rims | ART | - |
dc.citation.volume | 26 | - |
dc.citation.issue | 2 | - |
dc.citation.beginningpage | 95 | - |
dc.citation.endingpage | 103 | - |
dc.citation.publicationname | NEUROREHABILITATION | - |
dc.identifier.doi | 10.3233/NRE-2010-0540 | - |
dc.contributor.localauthor | Park C.-H. | - |
dc.contributor.nonIdAuthor | Park J.-W. | - |
dc.contributor.nonIdAuthor | Kim Y.-H. | - |
dc.contributor.nonIdAuthor | Jang S.H. | - |
dc.contributor.nonIdAuthor | Chang W.H. | - |
dc.contributor.nonIdAuthor | Kim S.T. | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Cortico-subcortical network | - |
dc.subject.keywordAuthor | functional MRI | - |
dc.subject.keywordAuthor | motor learning | - |
dc.subject.keywordPlus | POSITRON-EMISSION-TOMOGRAPHY | - |
dc.subject.keywordPlus | TRANSCRANIAL MAGNETIC STIMULATION | - |
dc.subject.keywordPlus | BRAIN ACTIVATION | - |
dc.subject.keywordPlus | VISUOMOTOR SEQUENCE | - |
dc.subject.keywordPlus | FUNCTIONAL-ANATOMY | - |
dc.subject.keywordPlus | SKILL ACQUISITION | - |
dc.subject.keywordPlus | PREMOTOR CORTEX | - |
dc.subject.keywordPlus | FRONTAL LOBES | - |
dc.subject.keywordPlus | CEREBELLUM | - |
dc.subject.keywordPlus | MOVEMENT | - |
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