Enhanced Protein Immobilization Efficiency on a TiO2 Surface Modified with a Hydroxyl Functional Group
An antibody immobilization was investigated using a self-assembled monolayer (SAM) over the highly refractive coatings with a SiO2, TiO2, or Si3N4 substrate. The immobilization was characterized by analyzing the hydrophilic properties of hydroxyl (OH) groups on Surface coatings with contact angle (CA) measurements to enhance protein immobilization. The hydroxyl (OH) group was formed in greater amounts its the oxygen plasma exposure time was increased, which resulted in a large enhancement in antibody immobilization. It indicated that hydroxyl (OH) group formation is critical for developing a label-free optical transducer with a high sensitivity.
- Publisher
- AMER CHEMICAL SOC
- Issue Date
- 2009
- Language
- English
- Article Type
- Article
- Keywords
SELF-ASSEMBLED MONOLAYERS; LOW-TEMPERATURE; DNA; PHOTOCATALYSIS; SPECTROSCOPY; MICROARRAYS; ADSORPTION; HYDROGEN; SENSORS; PHASE
- Citation
LANGMUIR, v.25, no.19, pp.11692 - 11697
- ISSN
- 0743-7463
- Appears in Collection
- RIMS Journal Papers
- Files in This Item
- There are no files associated with this item.
This item is cited by other documents in WoS
| ⊙ Detail Information in WoSⓡ | Click to see |  |
| ⊙ Cited 47 items in WoS | Click to see citing articles in |  |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.