DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yun, Kwang-Seok | ko |
dc.contributor.author | Yoon, Euisik | ko |
dc.date.accessioned | 2013-03-07T11:12:14Z | - |
dc.date.available | 2013-03-07T11:12:14Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2005-03 | - |
dc.identifier.citation | BIOMEDICAL MICRODEVICES, v.7, no.1, pp.35 - 40 | - |
dc.identifier.issn | 1387-2176 | - |
dc.identifier.uri | http://hdl.handle.net/10203/90031 | - |
dc.description.abstract | In this paper we have proposed and demonstrated a microfluidic device for a fast and parallel single-cell based assay. The proposed device is designed to passively capture single-cells or beads on multiple cell-positioning sites by a pre-defined fluidic stream and inject specific reagents or drugs onto each isolated single-cell. The device consists of surface-modified silicon channels capped with a grooved polydimethylsiloxane (PDMS) cover layer. A cell capture experiment has been performed using polystyrene beads as well as CHO DG44 living cells, and successful positioning of a single-cell on the cell-positioning sites was achieved. Also, we have demonstrated independent drug injection into a specific target cell. | - |
dc.language | English | - |
dc.publisher | SPRINGER | - |
dc.subject | CAPILLARY-ELECTROPHORESIS | - |
dc.subject | NEURAL-NETWORKS | - |
dc.subject | MANIPULATION | - |
dc.title | Micro/nanofluidic device for single-cell-based assay | - |
dc.type | Article | - |
dc.identifier.wosid | 000228503300004 | - |
dc.identifier.scopusid | 2-s2.0-18144418528 | - |
dc.type.rims | ART | - |
dc.citation.volume | 7 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 35 | - |
dc.citation.endingpage | 40 | - |
dc.citation.publicationname | BIOMEDICAL MICRODEVICES | - |
dc.identifier.doi | 10.1007/s10544-005-6169-5 | - |
dc.contributor.nonIdAuthor | Yoon, Euisik | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | lab-on-a-chip | - |
dc.subject.keywordAuthor | single-cell analysis | - |
dc.subject.keywordAuthor | cell capture | - |
dc.subject.keywordAuthor | drug screening | - |
dc.subject.keywordAuthor | surface modification | - |
dc.subject.keywordPlus | CAPILLARY-ELECTROPHORESIS | - |
dc.subject.keywordPlus | NEURAL-NETWORKS | - |
dc.subject.keywordPlus | MANIPULATION | - |
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