Intracellular drug delivery using poly(D,L-lactide-co-glycolide) nanoparticles derivatized with a peptide from a transcriptional activator protein of HIV-1
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Nam, YoonSung | ko |
| dc.contributor.author | Park, JY | ko |
| dc.contributor.author | Han, SH | ko |
| dc.contributor.author | Chang, IS | ko |
| dc.date.accessioned | 2013-03-04T20:54:55Z | - |
| dc.date.available | 2013-03-04T20:54:55Z | - |
| dc.date.created | 2012-03-19 | - |
| dc.date.created | 2012-03-19 | - |
| dc.date.issued | 2002-12 | - |
| dc.identifier.citation | BIOTECHNOLOGY LETTERS, v.24, no.24, pp.2093 - 2098 | - |
| dc.identifier.issn | 0141-5492 | - |
| dc.identifier.uri | http://hdl.handle.net/10203/84107 | - |
| dc.description.abstract | Biodegradable poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles were derivatized with Tat(49-57) peptide, which is the protein transduction domain from the transcriptional activator Tat protein of human immunodeficiency virus type-1 (HIV-1). The Tat(49-57) peptide-modified PLGA nanoparticles, with a mean diameter of ca. 238 nm, was effectively adsorbed on to the membrane of HaCaT cells and delivered into the nuclei without cytotoxicity. | - |
| dc.language | English | - |
| dc.publisher | SPRINGER | - |
| dc.subject | TOXICITY | - |
| dc.subject | THERAPY | - |
| dc.title | Intracellular drug delivery using poly(D,L-lactide-co-glycolide) nanoparticles derivatized with a peptide from a transcriptional activator protein of HIV-1 | - |
| dc.type | Article | - |
| dc.identifier.wosid | 000179636600013 | - |
| dc.identifier.scopusid | 2-s2.0-0036955764 | - |
| dc.type.rims | ART | - |
| dc.citation.volume | 24 | - |
| dc.citation.issue | 24 | - |
| dc.citation.beginningpage | 2093 | - |
| dc.citation.endingpage | 2098 | - |
| dc.citation.publicationname | BIOTECHNOLOGY LETTERS | - |
| dc.identifier.doi | 10.1023/A:1021373731787 | - |
| dc.contributor.localauthor | Nam, YoonSung | - |
| dc.contributor.nonIdAuthor | Park, JY | - |
| dc.contributor.nonIdAuthor | Han, SH | - |
| dc.contributor.nonIdAuthor | Chang, IS | - |
| dc.type.journalArticle | Article | - |
| dc.subject.keywordAuthor | biodegradable polymer | - |
| dc.subject.keywordAuthor | conjugates | - |
| dc.subject.keywordAuthor | nanoparticles | - |
| dc.subject.keywordAuthor | protein transduction domain (PTD) | - |
| dc.subject.keywordAuthor | Tat peptide | - |
| dc.subject.keywordPlus | TOXICITY | - |
| dc.subject.keywordPlus | THERAPY | - |
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