Monolayers of poly(alpha,beta-aspartic acid) with long alkyl chains and miscibility with L-alpha-phosphatidylcholine at air-water interface

Abstract

Surface pressure/area isotherms of polypeptides modified with long alkyl chains and their miscibility with DPPC were investigated. The modified polypeptides formed stable monolayers due to their hairy-rod structure and limiting area increased as the degree of substitution increased. Collapse pressure of mixed monolayers deviated from ideal mixture and the free energies of mixing were negative values in all composition.