DC Field | Value | Language |
---|---|---|
dc.contributor.author | Gadaginamath G.S. | ko |
dc.contributor.author | Pujar S.R. | ko |
dc.contributor.author | Donawade D.S. | ko |
dc.contributor.author | Kavali R.R. | ko |
dc.date.accessioned | 2013-03-04T00:02:37Z | - |
dc.date.available | 2013-03-04T00:02:37Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 2004 | - |
dc.identifier.citation | JOURNAL OF THE INDIAN CHEMICAL SOCIETY, v.81, no.10, pp.865 - 867 | - |
dc.identifier.issn | 0019-4522 | - |
dc.identifier.uri | http://hdl.handle.net/10203/80987 | - |
dc.description.abstract | When 1 -substituted-3,6-diacetyl-5-hydroxy-2-methylindoles 1(a,b) were reacted with ethyl acetoacetate in presence of 2-methylpiperidine produced new 6-substituted-3,8-diacetyl-4,7-dimethyl-2H-pyrano[6,5-f]indole-2-ones2(a,b). Then these compounds 2(a,b) were chemoselectively brominated with bromine in chloroform to generate exclusively, 6-substituted-3bromoacetyl-4,7-dimethyl-8-acetyl-2H-pyrano[6,5-f]indole-2-ones 3(a,b). Compounds 3(a,b) were then refluxed in dry ethanol with thiourea to secure 6-substituted 3-(2-aminothiazol-5-3,1)-8-acetyl-4,7-dimethyl-2H-pyrano[6,5-f]indole-2-ones 5(a, b). Similarly, o-hydroxyacetophenone 6 was heated with ethyl acetoacetate in presence of 2-methylpiperidine to get 3-acetyl-4methyl coumarin 7. The structures of' all these newly synthesised compounds have been confirmed by spectral and analytical data and the compounds have been screened for antibacterial and antifungal activities. | - |
dc.language | English | - |
dc.publisher | INDIAN CHEMICAL SOC | - |
dc.subject | ANTITUMOR AGENTS | - |
dc.subject | DERIVATIVES | - |
dc.title | Synthesis and antimicrobial activity of new linearly fused 6-substituted-3,8-diacetyl-4,7-dimethyl-2H-pyrano[6,5-f]indoles, their chemoselective bromination and synthesis of 3-thiazolylpyranoindoles | - |
dc.type | Article | - |
dc.identifier.wosid | 000225277000007 | - |
dc.identifier.scopusid | 2-s2.0-8444221898 | - |
dc.type.rims | ART | - |
dc.citation.volume | 81 | - |
dc.citation.issue | 10 | - |
dc.citation.beginningpage | 865 | - |
dc.citation.endingpage | 867 | - |
dc.citation.publicationname | JOURNAL OF THE INDIAN CHEMICAL SOCIETY | - |
dc.contributor.localauthor | Kavali R.R. | - |
dc.contributor.nonIdAuthor | Gadaginamath G.S. | - |
dc.contributor.nonIdAuthor | Pujar S.R. | - |
dc.contributor.nonIdAuthor | Donawade D.S. | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordPlus | ANTITUMOR AGENTS | - |
dc.subject.keywordPlus | DERIVATIVES | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.