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College of Engineering(공과대학)Dept. of Nuclear and Quantum Engineering(원자력및양자공학과)NE-Journal Papers(저널논문)

HIGH-DENSITY CELL-CULTURE BY MEMBRANE-BASED CELL RECYCLE

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dc.contributor.authorChang, Ho Namko
dc.contributor.authorik-keun yooko
dc.contributor.authorbeon soo kimko
dc.date.accessioned2013-02-25T18:37:19Z-
dc.date.available2013-02-25T18:37:19Z-
dc.date.created2012-02-06-
dc.date.created2012-02-06-
dc.date.issued1994-
dc.identifier.citationBIOTECHNOLOGY ADVANCES, v.12, no.3, pp.467 - 487-
dc.identifier.issn0734-9750-
dc.identifier.urihttp://hdl.handle.net/10203/64390-
dc.description.abstractEnhancement of productivity of a bioprocess necessitates continuous operation of bioreactors with high biomass concentrations than are possible in conventional batch, fed-batch or continuous modes of culture. Membrane-based cell recycle has been effectively used to maintain high cell concentrations in bioreactors. This review compares membrane-based cell recycle operation with other such high density cell culture systems as immobilized cell reactors and reactors with cell recycle by centrifugation or gravity sedimentation. A theoretical of production of primary and secondary metabolites in membrane-based recycle systems is presented. Operation of this type of system is discussed with examples from aerobic and anaerobic fermentations.-
dc.languageEnglish-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectHOLLOW-FIBER BIOREACTOR-
dc.subjectPRODUCTIVITY ETHANOL FERMENTATIONS-
dc.subjectHIGH-CONCENTRATION CULTIVATION-
dc.subjectCROSS-FLOW FILTRATION-
dc.subjectESCHERICHIA-COLI-
dc.subjectCLOSTRIDIUM-ACETOBUTYLICUM-
dc.subjectSACCHAROMYCES-CEREVISIAE-
dc.subjectRETENTION CULTURE-
dc.subjectZYMOMONAS-MOBILIS-
dc.subjectACID PRODUCTION-
dc.titleHIGH-DENSITY CELL-CULTURE BY MEMBRANE-BASED CELL RECYCLE-
dc.typeArticle-
dc.identifier.wosidA1994NZ71700001-
dc.identifier.scopusid2-s2.0-0028110779-
dc.type.rimsART-
dc.citation.volume12-
dc.citation.issue3-
dc.citation.beginningpage467-
dc.citation.endingpage487-
dc.citation.publicationnameBIOTECHNOLOGY ADVANCES-
dc.identifier.doi10.1016/0734-9750(94)90020-5-
dc.contributor.localauthorChang, Ho Nam-
dc.contributor.nonIdAuthorik-keun yoo-
dc.contributor.nonIdAuthorbeon soo kim-
dc.type.journalArticleReview-
dc.subject.keywordAuthorHIGH DENSITY CELL CULTURE-
dc.subject.keywordAuthorCELL RECYCLE-
dc.subject.keywordAuthorCELL RETENTION-
dc.subject.keywordAuthorBIOREACTORS-
dc.subject.keywordPlusHOLLOW-FIBER BIOREACTOR-
dc.subject.keywordPlusPRODUCTIVITY ETHANOL FERMENTATIONS-
dc.subject.keywordPlusHIGH-CONCENTRATION CULTIVATION-
dc.subject.keywordPlusCROSS-FLOW FILTRATION-
dc.subject.keywordPlusESCHERICHIA-COLI-
dc.subject.keywordPlusCLOSTRIDIUM-ACETOBUTYLICUM-
dc.subject.keywordPlusSACCHAROMYCES-CEREVISIAE-
dc.subject.keywordPlusRETENTION CULTURE-
dc.subject.keywordPlusZYMOMONAS-MOBILIS-
dc.subject.keywordPlusACID PRODUCTION-
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CBE-Journal Papers(저널논문)
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