Browse "BS-Journal Papers(저널논문)" by Author Lee, Gyun Min
Showing results 12 to 71 of 112
| Baicalein Reduces Oxidative Stress in CHO Cell Cultures and Improves Recombinant Antibody Productivity Ha, Tae Kwang; Hansen, Anders Holmgaard; Kol, Stefan; Kildegaard, Helene Faustrup; Lee, Gyun Min, Biotechnology Journal, v.13, no.3, 2018-03 |
| BIOTRANSFORMATION OF RIFAMYCIN-B TO RIFAMYCIN-S USING IMMOBILIZED WHOLE CELLS OF HUMICOLA SPP IN A FLUIDIZED-BED REACTOR Lee, Gyun Min; Choi, CY; Park, JM; Han, MH, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. BIOTECHNOLOGY, v.35 B, no.1, pp.3 - 10, 1985-03 |
| Bip Inducer X: an ER Stress Inhibitor for Enhancing Recombinant Antibody Production in CHO Cell Culture Ha, Tae Kwang; Hansen, Anders H.; Kildegaard, Helene F.; Lee, Gyun Min, BIOTECHNOLOGY JOURNAL, v.14, no.10, 2019-10 |
| Blockage of undesirable endocytosis of recombinant human growth/differentiation factor-5 in Chinese hamster ovary cell cultures requires heparin analogs with specific chain lengths Kim, Mi Gyeom; Lee, Gyun Min, BIOTECHNOLOGY JOURNAL, v.16, no.10, pp.2100227, 2021-10 |
| Case study on human alpha 1-antitrypsin: Recombinant protein titers obtained by commercial ELISA kits are inaccurate Hansen, Henning Gram; Kildegaard, Helene Faustrup; Lee, Gyun Min; Kol, Stefan, BIOTECHNOLOGY JOURNAL, v.11, no.12, pp.1648 - 1656, 2016-12 |
| CELL-CULTURE CONDITIONS DETERMINE THE ENHANCEMENT OF SPECIFIC MONOCLONAL-ANTIBODY PRODUCTIVITY OF CALCIUM ALGINATE-ENTRAPPED S3H5/GAMMA-2BA2 HYBRIDOMA CELLS Lee, Gyun Min; Chuck, AS; Palsson, BO, BIOTECHNOLOGY AND BIOENGINEERING, v.41, no.3, pp.330 - 340, 1993-02 |
| Chemical Inhibition of Autophagy: Examining Its Potential to Increase the Specific Productivity of Recombinant CHO Cell Lines Baek, Eric H; Kim, Che Lin; Kim, Mi Gyeom; Lee, Jae Seong; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.113, no.9, pp.1953 - 1961, 2016-09 |
| Co-amplification of EBNA-1 and PyLT through dhfr-mediated gene amplification for improving foreign protein production in transient gene expression in CHO cells Lee, Joohyoung; Park, Jong-Ho; Park, Sun-Hye; Kim, Sun-Hong; Kim, Jee-Yon; Min, Jeong-Ki; Lee, Gyun Min; et al, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.102, no.11, pp.4729 - 4739, 2018-06 |
| Combinatorial treatment with lithium chloride enhances recombinant antibody production in transiently transfected CHO and HEK293E cells Kim, Che Lin; Ha, Tae Kwang; Lee, Gyun Min, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.21, no.5, pp.667 - 675, 2016-09 |
| Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells Shin, Seunghyeon; Kim, Su Hyun; Shin, Sung Wook; Grav, Lise Marie; Pedersen, Lasse Ebdrup; Lee, Jae Seong; Lee, Gyun Min, ACS SYNTHETIC BIOLOGY, v.9, no.6, pp.1263 - 1269, 2020-06 |
| Comprehensive characterization of dihydrofolate reductase-mediated gene amplification for the establishment of recombinant human embryonic kidney 293 cells producing monoclonal antibodies Lee, Sang Yoon; Baek, Minhye; Lee, Gyun Min, BIOTECHNOLOGY JOURNAL, v.16, no.5, 2021-05 |
Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies Noh, Soo Min; Shin, Seunghyeon; Lee, Gyun Min, SCIENTIFIC REPORTS, v.8, no.5361, pp.1 - 11, 2018-03 |
| Comprehensive Physicochemical and Biological Characterization of the Proposed Biosimilar Darbepoetin Alfa, LBDE, and Its Originator Darbepoetin Alfa, NESPA (R) Jeong, Yeong Ran; Jeong, Rae Ung; Son, Jeong Hyun; Kwon, Joon Cheol; Jung, Saem; Song, Mi A.; Hwang, Jin Ah; et al, BIODRUGS, v.32, no.2, pp.153 - 168, 2018-04 |
| CONTINUOUS ETHANOL-PRODUCTION FROM SAGO STARCH USING IMMOBILIZED AMYLOGLUCOSIDASE AND ZYMOMONAS-MOBILIS Lee, Gyun Min; Kim, C.H.; Abidin, Z.; Han, M.H.; Rhee, S.K., JOURNAL OF FERMENTATION TECHNOLOGY, v.65, no.5, pp.531 - 535, 1987-12 |
| CRISPR/Cas9-Multiplexed Editing of Chinese Hamster Ovary B4Gal-T1, 2, 3, and 4 Tailors N-Glycan Profiles of Therapeutics and Secreted Host Cell Proteins Amann, Thomas; Hansen, Anders Holmgaard; Kol, Stefan; Lee, Gyun Min; Andersen, Mikael Rordam; Kildegaard, Helene Faustrup, BIOTECHNOLOGY JOURNAL, v.13, no.10, 2018-10 |
| Cytogenetic analysis of chimeric antibody-producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure Kim, S.J.; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.64, no.6, pp.741 - 749, 1999-09 |
| Decreased chimeric antibody productivity of KR12H-1 transfectoma during long-term culture results from decreased antibody gene copy number Kim, Jaehoon; Bae, Sung Won; Hong, Hyo Jeong; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.51, no.4, pp.479 - 487, 1996-08 |
| Development of a serum-free medium for dihydrofolate reductase-deficient Chinese hamster ovary cells (DG44) using a statistical design: Beneficial effect of weaning of cells Kim, EJ; Kim, NS; Lee, Gyun Min, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, v.35, no.4, pp.178 - 182, 1999-04 |
| Development of an in vitro screening system for synthetic signal peptide in mammalian cell-based protein production Park, Jong-Ho; Lee, Hoon-Min; Jin, Eun-Ju; Lee, Eun-Ji; Kang, Yeon-Ju; Kim, Sungkyun; Yoo, Sung-Sick; et al, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.106, no.9-10, pp.3571 - 3582, 2022-05 |
| Differential expression of microRNAs in recombinant Chinese hamster ovary cells treated with sodium butyrate using digital RNA counting Lim, Sung-Min; Park, Sun-Hye; Lee, Joohyoung; Kim, Sun Hong; Kim, Jee-Yon; Min, Jeong-Ki; Lee, Gyun Min; et al, JOURNAL OF BIOTECHNOLOGY, v.283, pp.37 - 42, 2018-10 |
| EFFECT OF ANCHORAGE DEPENDENCY ON GROWTH-RATE AND MONOCLONAL-ANTIBODY PRODUCTION OF HYBRIDOMA CELLS Lee, Gyun Min; Huard, Thomas K.; Palsson, Bernhard Ø, BIOTECHNOLOGY LETTERS, v.10, no.5, pp.307 - 312, 1988-12 |
| Effect of Bcl-x(L) overexpression on sialylation of Fc-fusion protein in recombinant Chinese hamster ovary cell cultures Lee, Jong Hyun; Kim, Yeon-Gu; Lee, Gyun Min, BIOTECHNOLOGY PROGRESS, v.31, no.4, pp.1133 - 1137, 2015-07 |
| EFFECT OF FIXATION TEMPERATURE ON FLOW CYTOMETRIC MEASUREMENT OF INTRACELLULAR ANTIBODY CONTENT OF HYBRIDOMAS DURING BATCH CULTURE Lee, Gyun Min; Chuck, AS; Palsson, BO, BIOTECHNOLOGY TECHNIQUES, v.7, no.4, pp.271 - 276, 1993-04 |
| Effect of glutamine substitution by TCA cycle intermediates on the production and sialylation of Fc-fusion protein in Chinese hamster ovary cell culture Ha, Tae Kwang; Lee, Gyun Min, JOURNAL OF BIOTECHNOLOGY, v.180, pp.23 - 29, 2014-06 |
| Effect of hypoosmotic stress on hybridoma cell growth and antibody production Ryu, J.S.; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.55, no.3, pp.565 - 570, 1997-08 |
| EFFECT OF MECHANICAL AGITATION ON HYBRIDOMA CELL-GROWTH Lee, Gyun Min; Huard, Thomas K.; Kaminski, Mark S.; Palsson, Bernhard Ø, BIOTECHNOLOGY LETTERS, v.10, no.9, pp.625 - 628, 1988-12 |
| Effect of mitochondrial and ER-targeted Bcl-2 overexpression on apoptosis in recombinant Chinese hamster ovary cells treated with sodium butyrate Kim, Yeon-Gu; Park, Byoungwoo; Lee, Seungwoon; Ahn, Jung Oh; Jung, Joon-Ki; Lee, Hong Weon; Lee, Gyun Min; et al, PROCESS BIOCHEMISTRY, v.47, no.12, pp.2518 - 2522, 2012-12 |
| EFFECT OF SERUM CONCENTRATION ON HYBRIDOMA CELL-GROWTH AND MONOCLONAL-ANTIBODY PRODUCTION AT VARIOUS INITIAL CELL DENSITIES Lee, Gyun Min; Huard, TK; Palsson, BO, HYBRIDOMA, v.8, no.3, pp.369 - 375, 1989-12 |
| Effect of serum concentration on retroviral vector production from the amphotropic psi CRIP murine producer cells JONG HYUN CHOI; SEUNG CHUL JUN; Lee, Gyun Min, BIOPROCESS ENGINEERING, v.17, no.6, pp.349 - 353, 1997-12 |
| Effect of serum type and concentration on the expression of beta-galactosidase in recombinant vaccinia virus infected HeLa S3 cells Seung Chul Jun; Lee, Gyun Min; Su Hwan Chang; Kim, Jung Hoe, CYTOTECHNOLOGY, v.19, no.2, pp.153 - 159, 1996 |
| EFFECT OF TRISODIUM CITRATE TREATMENT ON HYBRIDOMA CELL VIABILITY Lee, Gyun Min; Gray, JJ; Palsson, BO, BIOTECHNOLOGY TECHNIQUES, v.5, no.4, pp.295 - 298, 1991-07 |
| Efficient CRISPR/Cas9-mediated multiplex genome editing in CHO cells via high-level sgRNA-Cas9 complex Shin, Jongoh; Lee, Namil; Song, Yoseb; Park, Jinhyung; Kang, Taek Jin; Kim, Sun Chang; Lee, Gyun Min; et al, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.20, no.5, pp.825 - 833, 2015-09 |
| Endoplasmic reticulum-directed recombinant mRNA displays subcellular localization equal to endogenous mRNA during transient expression in CHO cells Kallehauge, Thomas Beuchert; Kol, Stefan; Andersen, Mikael Rordam; Damgaard, Christian Kroun; Lee, Gyun Min; Kildegaard, Helene Faustrup, BIOTECHNOLOGY JOURNAL, v.11, no.10, pp.1362 - 1367, 2016-10 |
| Enhanced cell growth, production, and mAb quality produced in Chinese hamster ovary-K1 cells by supplementing polyamine in the media Kang, Da Eun; An, Yeong Bin; Kim, Yeunju; Ahn, Seawon; Kim, Young Jin; Lim, Jung Soo; Ryu, Soo Hyun; et al, APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, v.107, no.9, pp.2855 - 2870, 2023-05 |
| ENHANCED SPECIFIC ANTIBODY PRODUCTIVITY OF CALCIUM ALGINATE-ENTRAPPED HYBRIDOMA IS CELL LINE-SPECIFIC Lee, Gyun Min; Kim, Sang Jick; Bernhard O. Palsson, CYTOTECHNOLOGY, v.16, no.1, pp.1 - 15, 1994-12 |
| ENHANCED SPECIFIC ANTIBODY PRODUCTIVITY OF HYBRIDOMAS RESULTING FROM HYPEROSMOTIC STRESS IS CELL LINE-SPECIFIC Lee, Gyun Min; Park, SY, BIOTECHNOLOGY LETTERS, v.17, no.2, pp.145 - 150, 1995-12 |
| ENHANCEMENT OF MONOCLONAL-ANTIBODY PRODUCTION BY IMMOBILIZED HYBRIDOMA CELL-CULTURE WITH HYPEROSMOLAR MEDIUM Sung Young Park; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.48, no.6, pp.699 - 705, 1995-12 |
| Enhancing CHO cell productivity through a dual selection system using Aspg and Gs in glutamine free medium Ha, Tae Kwang; Odena, Andreu; Karottki, Karen Julie la Cour; Kim, Che Lin; Hefzi, Hooman; Lee, Gyun Min; Faustrup Kildegaard, Helene; et al, BIOTECHNOLOGY AND BIOENGINEERING, v.120, no.4, pp.1159 - 1166, 2023-04 |
| ETHANOL-PRODUCTION FROM CASSAVA AND SAGO STARCH USING ZYMOMONAS-MOBILIS Rhee, S.K.; Lee, Gyun Min; Han, Y.T.; Zainal Abidin Mohd. Yusof; M. H. Han; K. J. Lee, BIOTECHNOLOGY LETTERS, v.6, no.9, pp.615 - 620, 1984-12 |
| EXPANSION OF HUMAN BONE-MARROW PROGENITOR CELLS IN A HIGH CELL-DENSITY CONTINUOUS PERFUSION SYSTEM Palsson, B.O.; Paek, S.H.; Schwartz, R.M.; Palsson, M.; Lee, Gyun Min; Silver, S.; Emerson, S.G., BIO-TECHNOLOGY , v.11, no.3, pp.368 - 372, 1993-12 |
| Expression and purification of recombinant human angiopoietin-1 produced in Chinese hamster ovary cells Hwang, Su-Jeong; Vim, Hak-Zoo; Koh, Gou Young; Lee, Gyun Min, IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, v.43, no.5-6, pp.162 - 167, 2007-05 |
| Factors affecting the quality of therapeutic proteins in recombinant Chinese hamster ovary cell culture Ha, Tae Kwang; Kim, Dongil; Kim, Che Lin; Grav, Lise Marie; Lee, Gyun Min, BIOTECHNOLOGY ADVANCES, v.54, 2022-01 |
| FEASIBILITY STUDY ON THE USE OF CALCIUM ALGINATE-ENTRAPPED HYBRIDOMA CELLS FOR IGM PRODUCTION Kim, SJ; Han, BK; Lee, Gyun Min, BIOPROCESS ENGINEERING, v.12, no.1-2, pp.65 - 70, 1995-12 |
| FEASIBILITY STUDY ON THE USE OF HYPEROSMOLAR MEDIUM FOR IMPROVED ANTIBODY-PRODUCTION OF HYBRIDOMA CELLS IN A LONG-TERM, REPEATED-FED BATCH CULTURE Park, Sung Young; Lee, Gyun Min, BIOPROCESS ENGINEERING, v.13, no.2, pp.79 - 86, 1995-12 |
| Forskolin Increases cAMP Levels and Enhances Recombinant Antibody Production in CHO Cell Cultures Yoon, Chansik; Kim, Dongil; Lim, Ju Hyeon; Lee, Gyun Min, BIOTECHNOLOGY JOURNAL, v.15, no.10, 2020-10 |
| Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion Gutierrez, Jahir M.; Feizi, Amir; Li, Shangzhong; Kallehauge, Thomas B.; Hefzi, Hooman; Grav, Lise M.; Ley, Daniel; et al, NATURE COMMUNICATIONS, v.11, no.1, pp.1 - 10, 2020-01 |
| Glutamine substitution: the role it can play to enhance therapeutic protein production Ha, Tae Kwang; Lee, Gyun Min, PHARMACEUTICAL BIOPROCESSING, v.3, no.3, pp.249 - 261, 2015 |
| Glutamine synthetase gene knockout-human embryonic kidney 293E cells for stable production of monoclonal antibodies Yu, Da Young; Lee, Sang Yoon; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.115, no.5, pp.1367 - 1372, 2018-05 |
| Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles Amann, Thomas; Hansen, Anders Holmgaard; Kol, Stefan; Hansen, Henning Gram; Arnsdorf, Johnny; Nallapareddy, Saranya; Voldborg, Bjorn; et al, METABOLIC ENGINEERING, v.52, pp.143 - 152, 2019-03 |
| Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Klionsky, Daniel J.; Abdelmohsen, Kotb; Abe, Akihisa; Abedin, Md Joynal; Lee, Gyun Min, AUTOPHAGY, v.12, no.1, pp.1 - 222, 2016 |
| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) Klionsky, Daniel J.; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; et al, AUTOPHAGY, v.17, no.1, pp.1 - 382, 2021-05 |
| Heparan sulfate proteoglycan synthesis in CHO DG44 and HEK293 cells Lee, Sojeong; Kim, Mi Gyeom; Kim, Nury; Heo, Won Do; Lee, Gyun Min, BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.21, no.3, pp.439 - 445, 2016-06 |
| Identification of hyperosmotic stress-responsive genes in Chinese hamster ovary cells via genome-wide virus-free CRISPR/Cas9 screening Kim, Su Hyun; Shin, Seunghyeon; Baek, Minhye; Xiong, Kai; Karottki, Karen Julie la Cour; Hefzi, Hooman; Grav, Lise Marie; et al, METABOLIC ENGINEERING, v.80, pp.66 - 77, 2023-11 |
| IMMOBILIZATION CAN IMPROVE THE STABILITY OF HYBRIDOMA ANTIBODY PRODUCTIVITY IN SERUM-FREE MEDIA Lee, Gyun Min; Palsson, BO, BIOTECHNOLOGY AND BIOENGINEERING, v.36, no.10, pp.1049 - 1055, 1990-12 |
| IMMOBILIZATION OF ZYMOMONAS-MOBILIS AND AMYLOGLUCOSIDASE FOR ETHANOL-PRODUCTION FROM SAGO STARCH Kim, C.H.; Lee, Gyun Min; Abidin, Z.; Han, M.H.; Rhee, S.K., ENZYME AND MICROBIAL TECHNOLOGY, v.10, no.7, pp.426 - 430, 1988-07 |
| Improving bone morphogenetic protein (BMP) production in CHO cells through understanding of BMP synthesis, signaling and endocytosis Kim, Kyungsoo; Kim, Mi Gyeom; Lee, Gyun Min, BIOTECHNOLOGY ADVANCES, v.62, 2023-01 |
| Improving recombinant bone morphogenetic protein-4 (BMP-4) production by autoregulatory feedback loop removal using BMP receptor-knockout CHO cell lines Kim, Che Lin; Lee, Gyun Min, METABOLIC ENGINEERING, v.52, pp.57 - 67, 2019-03 |
| Improving the production of recombinant human bone morphogenetic protein-4 in Chinese hamster ovary cell cultures by inhibition of undesirable endocytosis Kim, Che Lin; Jung, Mi Yeong; Kim, Young Sik; Jang, Ju Woong; Lee, Gyun Min, BIOTECHNOLOGY AND BIOENGINEERING, v.115, no.10, pp.2565 - 2575, 2018-10 |
| Improving the secretory capacity of Chinese hamster ovary cells by ectopic expression of effector genes: Lessons learned and future directions Hansen, Henning Gram; Pristovsek, Nusa; Kildegaard, Helene Faustrup; Lee, Gyun Min, BIOTECHNOLOGY ADVANCES, v.35, no.1, pp.64 - 76, 2017-01 |
| Improving the secretory capacity of CHO producer cells: The effect of controlled Blimp1 expression, a master transcription factor for plasma cells Kim, Su Hyun; Baek, Minhye; Park, Sungje; Shin, Seunghyeon; Lee, Jae Seong; Lee, Gyun Min, METABOLIC ENGINEERING, v.69, pp.73 - 86, 2022-01 |
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