DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 신현정 | - |
dc.contributor.author | Jeon, Young-Woo | - |
dc.contributor.author | 전영우 | - |
dc.date.accessioned | 2024-07-25T19:30:36Z | - |
dc.date.available | 2024-07-25T19:30:36Z | - |
dc.date.issued | 2023 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=1045593&flag=dissertation | en_US |
dc.identifier.uri | http://hdl.handle.net/10203/320493 | - |
dc.description | 학위논문(석사) - 한국과학기술원 : 기계공학과, 2023.8,[iii, 28 p. :] | - |
dc.description.abstract | Neural Stem Cells (NSCs) hold transformative potential in embryonic neurogenesis research, disease pathogenesis modeling, and drug-screening system design due to their capacity to differentiate into specific neuronal cells. Despite their promise, technical challenges pertaining to purity, reproducibility, and toxicity hinder the acquisition of high-quality Neural Progenitor Cells (NPCs). To address these challenges, this study utilizes morphology-based artificial intelligence (AI) analysis on neural rosette images to identify optimally conditioned cells. Our AI-driven morphological examination revealed distinct morphotypes within neural rosettes, a factor we found directly correlated with the reliability of neural induction during the neural differentiation process. These findings underline the considerable potential of morphology-based AI analysis as an innovative approach to enhance neural stem cell culture protocols, thereby providing meaningful contributions to the fields of neuroscience and cell biology. | - |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | 신경줄기세포▼a신경 로제트▼a인공지능기반 세포 분류▼a형태표현형 | - |
dc.subject | Neural Stem Cells (NSCs)▼aNeural rosettes▼aAI-based cell classification▼aMorphotypes | - |
dc.title | AI-based morphology analysis for evaluating neural differentiation and its application technologies | - |
dc.title.alternative | 신경줄기세포 분화 평가를 위한 AI 기반 형태 분석 및 응용 기술 | - |
dc.type | Thesis(Master) | - |
dc.identifier.CNRN | 325007 | - |
dc.description.department | 한국과학기술원 :기계공학과, | - |
dc.contributor.alternativeauthor | Shin, Hyun Jong | - |
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