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College of Engineering(공과대학)Dept. of Chemical and Biomolecular Engineering(생명화학공학과)CBE-Journal Papers(저널논문)

Programmable polyketide biosynthesis platform for production of aromatic compounds in yeast

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dc.contributor.authorJakociunas, Tadasko
dc.contributor.authorKlitgaard, Andreas K.ko
dc.contributor.authorKontou, Eftychia Evako
dc.contributor.authorNielsen, Julie Bangko
dc.contributor.authorThomsen, Emilko
dc.contributor.authorRomero-Suarez, Davidko
dc.contributor.authorBlin, Kaiko
dc.contributor.authorPetzold, Christopher J.ko
dc.contributor.authorGin, Jennifer W.ko
dc.contributor.authorTong, Yaojunko
dc.contributor.authorGotfredsen, Charlotte Heldko
dc.contributor.authorCharusanti, Pepko
dc.contributor.authorFrandsen, Rasmus J. N.ko
dc.contributor.authorWeber, Tilmannko
dc.contributor.authorLee, Sang Yupko
dc.contributor.authorJensen, Michael K.ko
dc.contributor.authorKeasling, Jay D.ko
dc.date.accessioned2020-04-01T07:20:04Z-
dc.date.available2020-04-01T07:20:04Z-
dc.date.created2020-03-18-
dc.date.created2020-03-18-
dc.date.created2020-03-18-
dc.date.created2020-03-18-
dc.date.issued2020-03-
dc.identifier.citationSYNTHETIC AND SYSTEMS BIOTECHNOLOGY, v.5, no.1, pp.11 - 18-
dc.identifier.issn2405-805X-
dc.identifier.urihttp://hdl.handle.net/10203/273751-
dc.description.abstractTo accelerate the shift to bio-based production and overcome complicated functional implementation of natural and artificial biosynthetic pathways to industry relevant organisms, development of new, versatile, bio-based production platforms is required. Here we present a novel yeast-based platform for biosynthesis of bacterial aromatic polyketides. The platform is based on a synthetic polyketide synthase system enabling a first demonstration of bacterial aromatic polyketide biosynthesis in a eukaryotic host.-
dc.languageEnglish-
dc.publisherKEAI PUBLISHING LTD-
dc.titleProgrammable polyketide biosynthesis platform for production of aromatic compounds in yeast-
dc.typeArticle-
dc.identifier.wosid000519089800002-
dc.identifier.scopusid2-s2.0-85078510384-
dc.type.rimsART-
dc.citation.volume5-
dc.citation.issue1-
dc.citation.beginningpage11-
dc.citation.endingpage18-
dc.citation.publicationnameSYNTHETIC AND SYSTEMS BIOTECHNOLOGY-
dc.identifier.doi10.1016/j.synbio.2020.01.004-
dc.contributor.localauthorLee, Sang Yup-
dc.contributor.nonIdAuthorJakociunas, Tadas-
dc.contributor.nonIdAuthorKlitgaard, Andreas K.-
dc.contributor.nonIdAuthorKontou, Eftychia Eva-
dc.contributor.nonIdAuthorNielsen, Julie Bang-
dc.contributor.nonIdAuthorThomsen, Emil-
dc.contributor.nonIdAuthorRomero-Suarez, David-
dc.contributor.nonIdAuthorBlin, Kai-
dc.contributor.nonIdAuthorPetzold, Christopher J.-
dc.contributor.nonIdAuthorGin, Jennifer W.-
dc.contributor.nonIdAuthorTong, Yaojun-
dc.contributor.nonIdAuthorGotfredsen, Charlotte Held-
dc.contributor.nonIdAuthorCharusanti, Pep-
dc.contributor.nonIdAuthorFrandsen, Rasmus J. N.-
dc.contributor.nonIdAuthorWeber, Tilmann-
dc.contributor.nonIdAuthorJensen, Michael K.-
dc.contributor.nonIdAuthorKeasling, Jay D.-
dc.description.isOpenAccessY-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorNatural products-
dc.subject.keywordAuthorSynthetic biology-
dc.subject.keywordAuthorAromatic polyketides-
dc.subject.keywordAuthorCRISPR/Cas9-
dc.subject.keywordAuthorPolyketide-
dc.subject.keywordAuthorProduction platform in eukaryotes-
dc.subject.keywordAuthorMetabolic engineering-
dc.subject.keywordAuthorBiotechnology-
dc.subject.keywordPlusENGINEERED BIOSYNTHESIS-
dc.subject.keywordPlusHYBRID ANTIBIOTICS-
dc.subject.keywordPlusACTINORHODIN-
dc.subject.keywordPlusIDENTIFICATION-
dc.subject.keywordPlusCRISPR/CAS9-
dc.subject.keywordPlusEXPRESSION-
dc.subject.keywordPlusSYNTHASES-
dc.subject.keywordPlusPATHWAY-
dc.subject.keywordPlusCLONING-
dc.subject.keywordPlusGENE-
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CBE-Journal Papers(저널논문)
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