DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | Kim, Yeuchun | - |
dc.contributor.advisor | 김유천 | - |
dc.contributor.author | Shin, Juhyung | - |
dc.date.accessioned | 2019-08-22T02:45:02Z | - |
dc.date.available | 2019-08-22T02:45:02Z | - |
dc.date.issued | 2018 | - |
dc.identifier.uri | http://library.kaist.ac.kr/search/detail/view.do?bibCtrlNo=867897&flag=dissertation | en_US |
dc.identifier.uri | http://hdl.handle.net/10203/264853 | - |
dc.description | 학위논문(박사) - 한국과학기술원 : 생명화학공학과, 2018.2,[v, 94 p. :] | - |
dc.description.abstract | The microneedle is delivery device suitable for intradermal drug delivery and can deliver a variety of drugs and vaccines. In this study, we have studied vaccine and protein delivery for microneedle as the main themes. First, various adjuvants were investigated to improve the immunogenicity of the vaccine delivered by the microneedle. Secondly, we investigated suitable viscosity enhancers and stabilizers in order to coat botulinum toxin on PLLA microneedle. In addition, we conducted a study to confirm whether the microneedle was suitable for the ferret, a representative model of influenza research. | - |
dc.language | eng | - |
dc.publisher | 한국과학기술원 | - |
dc.subject | Microneedle▼avaccine▼aadjuvant▼aformulation▼astability | - |
dc.subject | 마이크로니들▼a백신▼a애쥬번트▼a포뮬레이션▼a안정성 | - |
dc.title | Development of microneedle formulation for vaccine and protein application into skin | - |
dc.title.alternative | 피부 내 백신 및 단백질 전달을 위한 마이크로니들용 제형 연구 | - |
dc.type | Thesis(Ph.D) | - |
dc.identifier.CNRN | 325007 | - |
dc.description.department | 한국과학기술원 :생명화학공학과, | - |
dc.contributor.alternativeauthor | 신주형 | - |
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