Single step emulsification for the generation of multi-component double emulsions

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We successfully encapsulate two, three, and four different inner drops inside double emulsions by means of a single-step emulsification technique. The microfluidic device fabrication is simple and the emulsification process highly robust. Optical microscopy images of double emulsion generation and of monodisperse double emulsions with discrete numbers of inner drops indicate the achievement of a high level of control with this technique. When the middle fluid transitions from dripping to jetting, two additional variations of double emulsions are produced: highly packed double emulsions and double emulsions with different sizes of inner drops. Finally, we successfully coalesce inner drops confined in a wax shell by applying heat. This demonstrates that these multi-component double emulsions may be useful as micro-reactors.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2012-11
Language
English
Article Type
Article
Keywords

MONODISPERSE DOUBLE EMULSIONS; MEMBRANE EMULSIFICATION; MULTIPLE EMULSIONS; DRUG-DELIVERY; PARTICLES; SHELLS

Citation

SOFT MATTER, v.8, no.41, pp.10719 - 10724

ISSN
1744-683X
DOI
10.1039/c2sm25953b
URI
http://hdl.handle.net/10203/255323
Appears in Collection
CBE-Journal Papers(저널논문)
Files in This Item
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