A novel immobilization technique using a poly(amino acid) multilayer designed for surface plasmon resonance sensing

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dc.contributor.authorJeong, Jae Hyun-
dc.contributor.authorKim, Byoung Yun-
dc.contributor.authorLee, Seung Jun-
dc.contributor.authorKim, Jong-Duk-
dc.date.accessioned2011-09-14T06:16:38Z-
dc.date.available2011-09-14T06:16:38Z-
dc.date.issued2006-
dc.identifier.citationChemical Physics Letters, Vol.421, pp.373-377en
dc.identifier.issn0009-2614-
dc.identifier.urihttp://hdl.handle.net/10203/25178-
dc.description.abstractThe novel immobilization technique using a poly(amino acid) multilayer was designed for the SPR sensing platform. These poly(amino acid) multilayer was confirmed as a relatively hydrophilic surface with little tendency for nonspecific adsorption of biomolecules and a flat surface that the biomolecular interactions can occur uniformly on the sensing surface. The poly(amino acid) multilayer functionalized with biotin was investigated to control the surface density and to estimate the optimum space between ligands for effective SPR sensing. This multilayer study demonstrates the importance of surface density which is significantly sensitive for fabrication of surface functional group in the monitoring of kinetic phenomena.en
dc.description.sponsorshipThe authors are thankful for financial support from Ministry of Science and Technology through the strategic national R&D Program and partially the BK 21 project.en
dc.language.isoen_USen
dc.publisherElsevieren
dc.titleA novel immobilization technique using a poly(amino acid) multilayer designed for surface plasmon resonance sensingen
dc.typeArticleen
dc.identifier.doi10.1016/j.cplett.2006.01.098-
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