We have demonstrated epitaxial-based biaxially strained In0.53Ga0.47As metal-oxide-semiconductor field-effect transistors (MOSFETs). Tensile strained In0.53Ga0.47As MOSFETs shows a high peak mobility of 2150 cm(2)/Vs with the enhancement factor of 3.7 against Si MOSFETs. Furthermore, we have investigated the mobility enhancement mechanisms in the tensile strained In0.53Ga0.47As MOSFETs. It has been found that biaxial tensile strain is effective to enhance the electron mobility in InGaAs MOSFETs by an increase of inversion carrier density, which is caused by the modulation of conduction band minimum. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4714770]