DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임범혁 | ko |
dc.contributor.author | 박창균 | ko |
dc.contributor.author | 조현기 | ko |
dc.contributor.author | 임흥빈 | ko |
dc.date.accessioned | 2018-04-24T04:28:03Z | - |
dc.date.available | 2018-04-24T04:28:03Z | - |
dc.date.created | 2018-04-03 | - |
dc.date.created | 2018-04-03 | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | 한국약용작물학회지, v.25, no.4, pp.201 - 208 | - |
dc.identifier.issn | 1225-9306 | - |
dc.identifier.uri | http://hdl.handle.net/10203/241254 | - |
dc.description.abstract | Background: The present study was carried out to asses whether mulberry leaves (MLs) have the potential to inhibit the mutagenic effect of cigarette smoke condensates (CSCs). Methods and Results: ML powder was extracted with 70% ethanol, and a yield of 35.1% by weight was obtained. The 70% ethanol extract of ML was further extracted sequentially using diethyl ether, chloroform, butanol, dichloromethane and water. The crude 70% ethanol extract of MLs and its solvent fractions did not show any mutagenic effect when tested at concentrations up to 1 ㎎/ plate against Salmonella typhimurium TA98. In contrast, the crude 70% ethanol extract showed an inhibitory activity against the mutagenicity of CSCs in the presence of S-9 mixture. Among the solvent fractions, the diethyl ether fraction showed the highest inhibitory activity, which increased in a dose-dependent manner, inhibiting mutagenesis by approximately 97.1% at a concentration of 1 ㎎/plate. Conclusions: In this study, we found that a crude 70% ethanol extract of MLs and the diethyl ether fraction themselves are potentially not mutagenic, but inhibit the mutagenic effect of CSCs | - |
dc.language | English | - |
dc.publisher | 한국약용작물학회 | - |
dc.subject | Morus alba L. | - |
dc.subject | Salmonella typhimurium TA98 | - |
dc.subject | Antimutagenicity | - |
dc.subject | Ames Test | - |
dc.subject | Leaf Extract | - |
dc.subject | Safety | - |
dc.title | 뽕잎 추출물의 돌연변이 억제효과 | - |
dc.title.alternative | Antimutagenic Effect of Mulberry Leaf Extract | - |
dc.type | Article | - |
dc.type.rims | ART | - |
dc.citation.volume | 25 | - |
dc.citation.issue | 4 | - |
dc.citation.beginningpage | 201 | - |
dc.citation.endingpage | 208 | - |
dc.citation.publicationname | 한국약용작물학회지 | - |
dc.identifier.doi | 10.7783/KJMCS.2017.25.4.244 | - |
dc.identifier.kciid | ART002252663 | - |
dc.contributor.localauthor | 임범혁 | - |
dc.contributor.nonIdAuthor | 박창균 | - |
dc.contributor.nonIdAuthor | 조현기 | - |
dc.contributor.nonIdAuthor | 임흥빈 | - |
dc.description.isOpenAccess | N | - |
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