An ultrasensitive DNAzyme-based colorimetric strategy for nucleic acid detection

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An ultrasensitive DNAzyme-based colorimetric DNA detection strategy was developed by utilizing gold nanoparticles modified with both peroxidase-mimicking DNAzymes and capture DNAs and magnetic nanoparticles modified with another capture DNAs, with a detection limit for a model Chlamydia gene of 50 fM.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2009-06
Language
English
Article Type
Article
Keywords

TELOMERASE ACTIVITY; DNA-ENZYME; NANOPARTICLES; OLIGONUCLEOTIDES; INFECTIONS; DIAGNOSIS; CLEAVAGE; BEACONS; PROBES; GENE

Citation

CHEMICAL COMMUNICATIONS, no.39, pp.5838 - 5840

ISSN
1359-7345
DOI
10.1039/b907762f
URI
http://hdl.handle.net/10203/22757
Appears in Collection
CBE-Journal Papers(저널논문)
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