A plasmonic biosensor array by block copolymer lithography†

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Highly uniform and dense, hexagonal noble metal nanoparticle arrays were achieved on large-area transparent glass substrates via scalable, parallel processing of block copolymer lithography. Exploring their localized surface plasmon resonance (LSPR) characteristics revealed that the Ag nanoparticle array displayed a UV-vis absorbance spectrum sufficiently narrow and intense for biosensing application. A highly-sensitive, label-free detection of prostate cancer specific antibody (anti-PSA) with sub-ng ml1 level detection limit (0.11 ng ml1) has been accomplished with the plasmonic nanostructure. Our approach offers a valuable route to a low-cost, manufacture-scale production of plasmonic nanostructures, potentially useful for various photonic and optoelectronic devices.
Publisher
Royal Society of Chemistry
Issue Date
2010
Citation

Journal of Materials Chemistry, Vol.20

DOI
10.1039/c0jm01319f
URI
http://hdl.handle.net/10203/22739
Appears in Collection
MS-Journal Papers(저널논문)
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