A robust and quantitative assay platform for multiplexed, high throughput screening of protein kinase inhibitors

Cited 9 time in webofscience Cited 0 time in scopus
  • Hit : 507
  • Download : 0
We present a new platform for multiplexed protein kinase activity assay using TiO2 decorated graphene oxide (GO), which is applicable to high throughput inhibitor screening. On the basis of the strong affinity of TiO2 for the phosphate group and the fluorescence quenching capability of GO, phosphorylation of substrates by protein kinases was quantitatively measured in a short time
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2016-10
Language
English
Article Type
Article
Keywords

GRAPHENE OXIDE; MASS-SPECTROMETRY; PHOSPHORYLATION PROTECTION; HYBRID MATERIALS; CELLS; PHOSPHOPROTEOME; INFLAMMATION; BIOMOLECULES; ACTIVATION; BIOSENSOR

Citation

CHEMICAL COMMUNICATIONS, v.52, no.81, pp.12112 - 12115

ISSN
1359-7345
DOI
10.1039/c6cc05834e
URI
http://hdl.handle.net/10203/214146
Appears in Collection
CH-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 9 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0