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College of Natural Sciences(자연과학대학)Dept. of Chemistry(화학과)CH-Journal Papers(저널논문)

A robust and quantitative assay platform for multiplexed, high throughput screening of protein kinase inhibitors

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dc.contributor.authorLee, Jieonko
dc.contributor.authorPark, Il-Sooko
dc.contributor.authorPark, Ginamko
dc.contributor.authorCho, Kyu Kwangko
dc.contributor.authorPark, Hee-Sungko
dc.contributor.authorMin, Dal-Heeko
dc.date.accessioned2016-11-30T01:31:18Z-
dc.date.available2016-11-30T01:31:18Z-
dc.date.created2016-11-08-
dc.date.created2016-11-08-
dc.date.issued2016-10-
dc.identifier.citationCHEMICAL COMMUNICATIONS, v.52, no.81, pp.12112 - 12115-
dc.identifier.issn1359-7345-
dc.identifier.urihttp://hdl.handle.net/10203/214146-
dc.description.abstractWe present a new platform for multiplexed protein kinase activity assay using TiO2 decorated graphene oxide (GO), which is applicable to high throughput inhibitor screening. On the basis of the strong affinity of TiO2 for the phosphate group and the fluorescence quenching capability of GO, phosphorylation of substrates by protein kinases was quantitatively measured in a short time-
dc.languageEnglish-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectGRAPHENE OXIDE-
dc.subjectMASS-SPECTROMETRY-
dc.subjectPHOSPHORYLATION PROTECTION-
dc.subjectHYBRID MATERIALS-
dc.subjectCELLS-
dc.subjectPHOSPHOPROTEOME-
dc.subjectINFLAMMATION-
dc.subjectBIOMOLECULES-
dc.subjectACTIVATION-
dc.subjectBIOSENSOR-
dc.titleA robust and quantitative assay platform for multiplexed, high throughput screening of protein kinase inhibitors-
dc.typeArticle-
dc.identifier.wosid000385156700024-
dc.identifier.scopusid2-s2.0-84990060408-
dc.type.rimsART-
dc.citation.volume52-
dc.citation.issue81-
dc.citation.beginningpage12112-
dc.citation.endingpage12115-
dc.citation.publicationnameCHEMICAL COMMUNICATIONS-
dc.identifier.doi10.1039/c6cc05834e-
dc.contributor.localauthorPark, Hee-Sung-
dc.contributor.nonIdAuthorLee, Jieon-
dc.contributor.nonIdAuthorPark, Il-Soo-
dc.contributor.nonIdAuthorPark, Ginam-
dc.contributor.nonIdAuthorMin, Dal-Hee-
dc.type.journalArticleArticle-
dc.subject.keywordPlusGRAPHENE OXIDE-
dc.subject.keywordPlusMASS-SPECTROMETRY-
dc.subject.keywordPlusPHOSPHORYLATION PROTECTION-
dc.subject.keywordPlusHYBRID MATERIALS-
dc.subject.keywordPlusCELLS-
dc.subject.keywordPlusPHOSPHOPROTEOME-
dc.subject.keywordPlusINFLAMMATION-
dc.subject.keywordPlusBIOMOLECULES-
dc.subject.keywordPlusACTIVATION-
dc.subject.keywordPlusBIOSENSOR-
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CH-Journal Papers(저널논문)
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