DC Field | Value | Language |
---|---|---|
dc.contributor.author | Waltemath, Dagmar | ko |
dc.contributor.author | Karr, Jonathan R | ko |
dc.contributor.author | Bergmann, Frank T | ko |
dc.contributor.author | Lee, Daewon | ko |
dc.contributor.author | Song, Je-Hoon | ko |
dc.date.accessioned | 2016-11-09T06:58:53Z | - |
dc.date.available | 2016-11-09T06:58:53Z | - |
dc.date.created | 2016-10-31 | - |
dc.date.created | 2016-10-31 | - |
dc.date.issued | 2016-10 | - |
dc.identifier.citation | IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, v.63, no.10, pp.2007 - 2014 | - |
dc.identifier.issn | 0018-9294 | - |
dc.identifier.uri | http://hdl.handle.net/10203/213932 | - |
dc.description.abstract | Objective: Whole-cell (WC) modeling is a promising tool for biological research, bioengineering, and medicine. However, substantial work remains to create accurate comprehensive models of complex cells. Methods: We organized the 2015 Whole-Cell Modeling Summer School to teach WC modeling and evaluate the need for new WC modeling standards and software by recoding a recently published WC model in the Systems Biology Markup Language. Results: Our analysis revealed several challenges to representing WC models using the current standards. Conclusion: We, therefore, propose several new WC modeling standards, software, and databases. Significance: We anticipate that these new standards and software will enable more comprehensive models. | - |
dc.language | English | - |
dc.publisher | IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC | - |
dc.subject | MARKUP LANGUAGE SBML | - |
dc.subject | LEVEL 3 | - |
dc.subject | SYSTEMS | - |
dc.subject | RECONSTRUCTION | - |
dc.subject | CONSTRAINTS | - |
dc.subject | SIMULATION | - |
dc.subject | MAPS | - |
dc.title | Toward Community Standards and Software for Whole-Cell Modeling | - |
dc.type | Article | - |
dc.identifier.wosid | 000384570200004 | - |
dc.identifier.scopusid | 2-s2.0-84993897548 | - |
dc.type.rims | ART | - |
dc.citation.volume | 63 | - |
dc.citation.issue | 10 | - |
dc.citation.beginningpage | 2007 | - |
dc.citation.endingpage | 2014 | - |
dc.citation.publicationname | IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING | - |
dc.identifier.doi | 10.1109/TBME.2016.2560762 | - |
dc.contributor.nonIdAuthor | Waltemath, Dagmar | - |
dc.contributor.nonIdAuthor | Karr, Jonathan R | - |
dc.contributor.nonIdAuthor | Bergmann, Frank T | - |
dc.description.isOpenAccess | Y | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Computational biology | - |
dc.subject.keywordAuthor | education | - |
dc.subject.keywordAuthor | simulation | - |
dc.subject.keywordAuthor | standards | - |
dc.subject.keywordAuthor | systems biology | - |
dc.subject.keywordAuthor | whole-cell (WC) modeling | - |
dc.subject.keywordPlus | MARKUP LANGUAGE SBML | - |
dc.subject.keywordPlus | LEVEL 3 | - |
dc.subject.keywordPlus | SYSTEMS | - |
dc.subject.keywordPlus | RECONSTRUCTION | - |
dc.subject.keywordPlus | CONSTRAINTS | - |
dc.subject.keywordPlus | SIMULATION | - |
dc.subject.keywordPlus | MAPS | - |
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