DC Field | Value | Language |
---|---|---|
dc.contributor.author | Liu, KH | ko |
dc.contributor.author | Hwang, Soo-Jeong | ko |
dc.date.accessioned | 2016-07-05T08:16:38Z | - |
dc.date.available | 2016-07-05T08:16:38Z | - |
dc.date.created | 2016-05-31 | - |
dc.date.created | 2016-05-31 | - |
dc.date.issued | 2016-06 | - |
dc.identifier.citation | JOURNAL OF PERIODONTAL RESEARCH, v.51, no.3, pp.366 - 375 | - |
dc.identifier.issn | 0022-3484 | - |
dc.identifier.uri | http://hdl.handle.net/10203/209293 | - |
dc.description.abstract | Background and ObjectiveThe aim of this 12 mo prospective study was to assess the effect of smoking cessation on periodontal tissue without periodontal intervention, using matrix metalloproteinase (MMP)-8, MMP-9 and interleukin (IL)-1 ss in gingival crevicular fluid, and nicotine and cotinine in saliva. Material and MethodsOf the 122 male smokers enrolled in a smoking cessation clinic, 11 quitters, nine non-quitters, six oscillators and 13 non-smokers participated in all experiments done at follow-up week 2, and follow-up months 2, 4, 6 and 12. The following were measured: gingival index; dental plaque index and sites of 3.5 mm < probing depth < 5.5 mm using a WHO probe for the full mouth; amounts of MMP-8, MMP-9 and IL-1 in gingival crevicular fluid of the upper anterior teeth area using enzyme-linked immunosorbent assay; and concentrations of nicotine, cotinine and hydroxycotinine in saliva using high-performance liquid chromatography-tandem mass spectrometry. ResultsNo significant differences in MMP-8 and MMP-9 in gingival crevicular fluid were detected between smokers, quit-smokers, oscillators and non-smokers for 1 year. Only the amount of IL-1 showed that smokers (90.14 65.32 pg/mL) had a significantly higher value compared with non-smokers (37.70 +/- 40.90 pg/mL), quit-smokers (32.11 +/- 40.50 pg/mL) and oscillators (11.90 +/- 12.46 pg/mL) at 2 mo follow-up (p = 0.007). IL-1 had a positive correlation with nicotine (r = 0.351) and the cotinine (r = 0.376), nicotine (r = 0.492) and hydroxycotinine (r = 0.358), and hydroxycotinine (r = 0.413) levels at 2 wk and 4 and 6 mo follow-up, respectively. ConclusionsThis 1-year prospective smoking cessation study without nonsurgical periodontal therapy shows IL-1 in gingival crevicular fluid could have a positive relationship with the nicotine and cotinine levels in saliva | - |
dc.language | English | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.subject | ENVIRONMENTAL TOBACCO-SMOKE | - |
dc.subject | MATRIX METALLOPROTEINASES | - |
dc.subject | CIGARETTE-SMOKE | - |
dc.subject | RISK-FACTORS | - |
dc.subject | ORAL-HEALTH | - |
dc.subject | COLLAGEN DEGRADATION | - |
dc.subject | LIGAMENT CELLS | - |
dc.subject | IN-VITRO | - |
dc.subject | NICOTINE | - |
dc.subject | DISEASE | - |
dc.title | Effect of smoking cessation for 1 year on periodontal biomarkers in gingival crevicular fluid | - |
dc.type | Article | - |
dc.identifier.wosid | 000374989200011 | - |
dc.identifier.scopusid | 2-s2.0-84941585241 | - |
dc.type.rims | ART | - |
dc.citation.volume | 51 | - |
dc.citation.issue | 3 | - |
dc.citation.beginningpage | 366 | - |
dc.citation.endingpage | 375 | - |
dc.citation.publicationname | JOURNAL OF PERIODONTAL RESEARCH | - |
dc.identifier.doi | 10.1111/jre.12316 | - |
dc.contributor.nonIdAuthor | Liu, KH | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | gingival crevicular fluid | - |
dc.subject.keywordAuthor | IL-1 beta | - |
dc.subject.keywordAuthor | MMP-8 | - |
dc.subject.keywordAuthor | MMP-9 | - |
dc.subject.keywordAuthor | smoking | - |
dc.subject.keywordPlus | ENVIRONMENTAL TOBACCO-SMOKE | - |
dc.subject.keywordPlus | MATRIX METALLOPROTEINASES | - |
dc.subject.keywordPlus | CIGARETTE-SMOKE | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | ORAL-HEALTH | - |
dc.subject.keywordPlus | COLLAGEN DEGRADATION | - |
dc.subject.keywordPlus | LIGAMENT CELLS | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | NICOTINE | - |
dc.subject.keywordPlus | DISEASE | - |
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