DC Field | Value | Language |
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dc.contributor.author | Park, Ji Young | ko |
dc.contributor.author | Rha, Seung-Woon | ko |
dc.contributor.author | Choi, Byoung Geol | ko |
dc.contributor.author | Choi, Se Yeon | ko |
dc.contributor.author | Choi, Jae Woong | ko |
dc.contributor.author | Ryu, Sung Kee | ko |
dc.contributor.author | Lee, Se Tin | ko |
dc.contributor.author | Kim, Seunghwan | ko |
dc.contributor.author | Noh, Yung-Kyun | ko |
dc.contributor.author | Akkala, Raghavender Goud | ko |
dc.contributor.author | Li, Hu | ko |
dc.contributor.author | Ali, Jabar | ko |
dc.contributor.author | Kirn, Ji Bak | ko |
dc.contributor.author | Lee, Sunki | ko |
dc.contributor.author | Na, Jin Oh | ko |
dc.contributor.author | Choi, Cheol Ung | ko |
dc.contributor.author | Lim, Hong Euy | ko |
dc.contributor.author | Kim, Jin Won | ko |
dc.contributor.author | Kim, Eung Ju | ko |
dc.contributor.author | Park, Chang Gyu | ko |
dc.contributor.author | Seo, Hong Seog | ko |
dc.contributor.author | Oh, Dong Too | ko |
dc.date.accessioned | 2016-06-07T09:05:21Z | - |
dc.date.available | 2016-06-07T09:05:21Z | - |
dc.date.created | 2016-02-01 | - |
dc.date.created | 2016-02-01 | - |
dc.date.issued | 2016-01 | - |
dc.identifier.citation | YONSEI MEDICAL JOURNAL, v.57, no.1, pp.180 - 186 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | http://hdl.handle.net/10203/207737 | - |
dc.description.abstract | Purpose: Angiotensin converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) are associated with a decreased incidence of new-onset diabetes mellitus (NODM). The aim of this study was to compare the protective effect of ACEI versus ARBs on NODM in an Asian population. Materials and Methods: We investigated a total of 2817 patients who did not have diabetes mellitus from January 2004 to September 2009. To adjust for potential confounders, a propensity score matched (PSM) analysis was performed using a logistic regression model. The primary end-point was the cumulative incidence of NODM, which was defined as having a fasting blood glucose 126 mg/dL or HbAlc >= 6.5%. Multivariable cox-regression analysis was performed to determine the impact of ACEI versus ARB on the incidence of NODM. Results: Mean follow-up duration was 1839 1019 days in all groups before baseline adjustment and 1864 1034 days in the PSM group. After PSM (C-statistics=0.731), a total 1024 patients (ACEI group, n=512 and ARB group, n=512) were enrolled for analysis and baseline characteristics were well balanced. After PSM, the cumulative incidence of NODM at 3 years was lower in the ACEI group than the ARB group (2.1% vs. 5.0%, p=0.012). In multivariate analysis, ACEI vs. ARB was an independent predictor of the lower incidence for NODM (odd ratio 0.37, confidence interval 0.17-0.79, p=0.010). Conclusion: In the present study, compared with ARB, chronic ACEI administration appeared to be associated with a lower incidence of NODM in a series of Asian cardiovascular patients. | - |
dc.language | English | - |
dc.publisher | YONSEI UNIV COLL MEDICINE | - |
dc.subject | CARDIOVASCULAR-DISEASE | - |
dc.subject | INSULIN-RESISTANCE | - |
dc.subject | SYSTEM | - |
dc.title | Impact of Angiotensin Converting Enzyme Inhibitor versus Angiotensin Receptor Blocker on Incidence of New-Onset Diabetes Mellitus in Asians | - |
dc.type | Article | - |
dc.identifier.wosid | 000367632100024 | - |
dc.identifier.scopusid | 2-s2.0-84949818552 | - |
dc.type.rims | ART | - |
dc.citation.volume | 57 | - |
dc.citation.issue | 1 | - |
dc.citation.beginningpage | 180 | - |
dc.citation.endingpage | 186 | - |
dc.citation.publicationname | YONSEI MEDICAL JOURNAL | - |
dc.identifier.doi | 10.3349/ymj.2016.57.1.180 | - |
dc.contributor.nonIdAuthor | Park, Ji Young | - |
dc.contributor.nonIdAuthor | Rha, Seung-Woon | - |
dc.contributor.nonIdAuthor | Choi, Byoung Geol | - |
dc.contributor.nonIdAuthor | Choi, Se Yeon | - |
dc.contributor.nonIdAuthor | Choi, Jae Woong | - |
dc.contributor.nonIdAuthor | Ryu, Sung Kee | - |
dc.contributor.nonIdAuthor | Lee, Se Tin | - |
dc.contributor.nonIdAuthor | Kim, Seunghwan | - |
dc.contributor.nonIdAuthor | Akkala, Raghavender Goud | - |
dc.contributor.nonIdAuthor | Li, Hu | - |
dc.contributor.nonIdAuthor | Ali, Jabar | - |
dc.contributor.nonIdAuthor | Kirn, Ji Bak | - |
dc.contributor.nonIdAuthor | Lee, Sunki | - |
dc.contributor.nonIdAuthor | Na, Jin Oh | - |
dc.contributor.nonIdAuthor | Choi, Cheol Ung | - |
dc.contributor.nonIdAuthor | Lim, Hong Euy | - |
dc.contributor.nonIdAuthor | Kim, Jin Won | - |
dc.contributor.nonIdAuthor | Kim, Eung Ju | - |
dc.contributor.nonIdAuthor | Park, Chang Gyu | - |
dc.contributor.nonIdAuthor | Seo, Hong Seog | - |
dc.contributor.nonIdAuthor | Oh, Dong Too | - |
dc.description.isOpenAccess | Y | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Angiotensin converting enzyme inhibitor | - |
dc.subject.keywordAuthor | angiotensin receptor blocker | - |
dc.subject.keywordAuthor | diabetes mellitus | - |
dc.subject.keywordPlus | CARDIOVASCULAR-DISEASE | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | SYSTEM | - |
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