One new phenylglycoside, 1-hydroxy-3,4,5-trimethoxyphenyl-1-O-[6'-O-(4aEuro(3)-carboxy-1aEuro(3) ,3aEuro(3) ,5aEuro(3) - trihydroxy)phenyl]-beta-D-glucopyranoside (1), along with eight known ones, isosalicin (2), vanilloloside (3), (4-hydroxy-3,5-dimethoxyphenyl)methyl-beta-D-glucopyranoside (4), crenatin (5), hydrageifolin I (6), tachioside (7), isotachioside (8), and koaburside (9), were isolated from the stems of Spiraea prunifolia var. simpliciflora. The chemical structures of these compounds were identified on the basis of spectroscopic data such as NMR, FAB-MS, and IR. All these compounds were isolated from this plant for the first time.