주파수분석법과 비선형동역학분석법을 이용한 한국 성인의 단기 맥박변이율(PRV)에 대한 연구

Abstract

A Study of the Short-Term Pulse Rate Variability Using Frequency and Nonlinear Dynamic Analyses Techniques in the Korean AdultsJang, Dae-Geun1 Shin, Sunghoon2* Park, Seung-Hun3AbstractThe aim of the study was to investigate the Korean adults’ short-term pulse rate variabilities (PRV) using the frequency and nonlinear analyses techniques. In this study, we utilized 336 photoplethysmogram (PPG) signals obtained for one-minute. For the frequency PRV analysis, three well-known quantitative parameters were used: the normalized low frequency (LFnorm) power, the normalized high frequency (HFnorm) power, and the LF/HF ratio. As nonlinear dynamic measures, the standard deviation (SD) ratio, the dimension spectrum with order of 2, the Higuchi’s fractal dimension, and the approximate entropy were used. The PRV parameters were evaluated by the multiple linear regression analysis with independent variables of age, sex, BMI, exercise status, familiar cardiovascular disease history, hypertension status, and heart rate. The variables of sex, exercise status, and familial cardiovascular disease history were used as dummy variables. The results show that regression models with each PRV parameter are statistically significant (p<.001). In particular, the regression model with the approximate entropy shows the highest coefficient of determination (R2) among the regression models. The results further indicate that the short-term PRV parameters are significantly correlated with subjects’ age and sex. Therefore, we conclude that the PRV parameters derived from the short-term PP intervals are proper to investigate the Korean adults’ cardiovascular-autonomic characteristics.