DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Dong Yun | ko |
dc.contributor.author | Lee, Chang Hwan | ko |
dc.contributor.author | Seo, Min Jung | ko |
dc.contributor.author | Lee, Suk Hyun | ko |
dc.contributor.author | Ryu, Jin-Sook | ko |
dc.contributor.author | Lee, Jong Jin | ko |
dc.date.accessioned | 2015-11-20T09:52:00Z | - |
dc.date.available | 2015-11-20T09:52:00Z | - |
dc.date.created | 2014-12-01 | - |
dc.date.created | 2014-12-01 | - |
dc.date.issued | 2014-10 | - |
dc.identifier.citation | ANNALS OF NUCLEAR MEDICINE, v.28, no.8, pp.789 - 795 | - |
dc.identifier.issn | 0914-7187 | - |
dc.identifier.uri | http://hdl.handle.net/10203/201139 | - |
dc.description.abstract | Objective The purpose of this study was to investigate the diagnostic performance of postoperative fluorine-18 fluoro-2-deoxy-D-glucose (F-18-FDG) positron emission tomography/computed tomography (PET/CT) as a surveillance modality for advanced gastric cancer patients who were asymptomatic and negative by conventional follow-up. Methods We retrospectively collected 46 advanced gastric cancer patients who received approximately 1-year-postoperative F-18-FDG PET/CT surveillance following curative resection (mean age 60.6 +/- 11.5 years). F-18-FDG PET/CT was interpreted by nuclear medicine physicians who were blind to the clinical information. Final confirmation was determined by clinical follow-up using tumor markers, conventional CT scan, upper gastrointestinal endoscopy and with/without subsequent histopathologic diagnosis. Results Four patients developed recurrence (8.7 %; 1 local and 3 distant recurrences). For local recurrence, F-18-FDG PET/CT found four hypermetabolic lesions and one was local recurrence. For distant recurrence, seven hypermetabolic lesions were found in six patients and true-positive was three lesions. False-positive cases were mainly turned out to be physiologic small bowel uptake. Regardless of the recurrence site, the sensitivity, specificity, positive predictive value and negative predictive value of F-18-FDG PET/CT were 100 % (4/4, 95 % confidence interval (CI) 39.6-100 %), 88.1 % (37/42, 95 % CI 73.6-95.5 %), 44.4 % (4/9, 95 % CI 15.3-77.3 %) and 100 % (37/37, 95 % CI 88.3-100 %), respectively in the patient-based analysis. Conclusion Our study showed good specificity of postoperative surveillance F-18-FDG PET/CT for detecting recurrence. Careful caution should be made for interpreting some false-positive hypermetabolic lesions in postoperative F-18-FDG PET/CT, especially at the local anastomosis site. | - |
dc.language | English | - |
dc.publisher | SPRINGER | - |
dc.subject | FDG PET/CT | - |
dc.subject | FOLLOW-UP | - |
dc.subject | CURATIVE RESECTION | - |
dc.subject | RECURRENCE | - |
dc.subject | CT | - |
dc.subject | GASTRECTOMY | - |
dc.subject | TOMOGRAPHY | - |
dc.title | Performance of F-18-FDG PET/CT as a postoperative surveillance imaging modality for asymptomatic advanced gastric cancer patients | - |
dc.type | Article | - |
dc.identifier.wosid | 000343921400009 | - |
dc.identifier.scopusid | 2-s2.0-84919873602 | - |
dc.type.rims | ART | - |
dc.citation.volume | 28 | - |
dc.citation.issue | 8 | - |
dc.citation.beginningpage | 789 | - |
dc.citation.endingpage | 795 | - |
dc.citation.publicationname | ANNALS OF NUCLEAR MEDICINE | - |
dc.identifier.doi | 10.1007/s12149-014-0871-4 | - |
dc.contributor.nonIdAuthor | Lee, Chang Hwan | - |
dc.contributor.nonIdAuthor | Seo, Min Jung | - |
dc.contributor.nonIdAuthor | Lee, Suk Hyun | - |
dc.contributor.nonIdAuthor | Ryu, Jin-Sook | - |
dc.contributor.nonIdAuthor | Lee, Jong Jin | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Advanced gastric cancer | - |
dc.subject.keywordAuthor | Asymptomatic | - |
dc.subject.keywordAuthor | F-18-FDG PET/CT | - |
dc.subject.keywordAuthor | Surveillance | - |
dc.subject.keywordAuthor | Postoperative | - |
dc.subject.keywordAuthor | Recurrence | - |
dc.subject.keywordPlus | FDG PET/CT | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | CURATIVE RESECTION | - |
dc.subject.keywordPlus | RECURRENCE | - |
dc.subject.keywordPlus | CT | - |
dc.subject.keywordPlus | GASTRECTOMY | - |
dc.subject.keywordPlus | TOMOGRAPHY | - |
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