Microneedle applications for DNA vaccine delivery to the skin

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dc.contributor.authorSeok, Hae Yongko
dc.contributor.authorSuh, Hyemeeko
dc.contributor.authorBaek, Sunghyunko
dc.contributor.authorKim, Yeu Chunko
dc.date.accessioned2015-06-24T02:23:40Z-
dc.date.available2015-06-24T02:23:40Z-
dc.date.created2015-06-11-
dc.date.created2015-06-11-
dc.date.issued2014-
dc.identifier.citationMETHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.), v.1143, pp.141 - 158-
dc.identifier.issn1064-3745-
dc.identifier.urihttp://hdl.handle.net/10203/199008-
dc.description.abstractMicroneedles were initially developed as pretreatment tools for the delivery of therapeutic drugs to intradermal locales in the human skin. Over time, variations in microneedle forms and functions burgeoned through the works of many researchers worldwide. The four major types of microneedles in use today are solid, dissolving, coating, and hollow microneedles. The emergence of different types of microneedles also paved the way for a flourishing diversification of microneedle applications, one of the most remarkable of which deals with the transcutaneous delivery of prophylactic vaccines. Here, we describe fabrication methods of microneedles and DNA vaccine loading methods on the microneedle surface. Furthermore, in the latter part of this chapter, in vivo test protocols for assessing the efficacy of gene delivery using microneedles are described.-
dc.languageEnglish-
dc.publisherHumana Press, Inc.-
dc.titleMicroneedle applications for DNA vaccine delivery to the skin-
dc.typeArticle-
dc.identifier.scopusid2-s2.0-84921321373-
dc.type.rimsART-
dc.citation.volume1143-
dc.citation.beginningpage141-
dc.citation.endingpage158-
dc.citation.publicationnameMETHODS IN MOLECULAR BIOLOGY (CLIFTON, N.J.)-
dc.identifier.doi10.1007/978-1-4939-0410-5_10-
dc.contributor.localauthorKim, Yeu Chun-
dc.contributor.nonIdAuthorSuh, Hyemee-
dc.contributor.nonIdAuthorBaek, Sunghyun-
dc.subject.keywordAuthorDNA vaccine-
dc.subject.keywordAuthorElectroporation-
dc.subject.keywordAuthorGene delivery-
dc.subject.keywordAuthorMicroneedle-
dc.subject.keywordAuthorNanoparticle-
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CBE-Journal Papers(저널논문)
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