Biorefineries for the production of top building block chemicals and their derivatives

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Due to the growing concerns on the climate change and sustainability on petrochemical resources, DOE selected and announced the bio-basecl top 12 building blocks and discussed the needs for developing biorefinery technologies to replace the current petroleum based industry in 2004. Over the last 10 years after its announcement, many studies have been performed for the development of efficient technologies for the bio-based production of these chemicals and derivatives. Now, ten chemicals among these Lop 12 chemicals, excluding the L-aspartic acid and 3-hydroxybutyrolactone, have already been commercialized or are close to commercialization. In this paper, we review the current status of biorefinery development for the production of these platform chemicals and their derivatives. In addition, current technological advances on industrial strain development for the production of platform chemicals using micro-organisms will be covered in detail with case studies on succinic acid and 3-hydroxypropionic acid as examples.
Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
Issue Date
2015-03
Language
English
Article Type
Review
Citation

METABOLIC ENGINEERING, v.28, pp.223 - 239

ISSN
1096-7176
DOI
10.1016/j.ymben.2014.12.007
URI
http://hdl.handle.net/10203/196091
Appears in Collection
CBE-Journal Papers(저널논문)
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