Aptamer-based cell imaging reagents capable of fluorescence switching

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We describe an aptamer-conjugated polydiacetylene imaging probe (ACP) that shows highly specific fluorescence switching upon binding to epithelial cancer cells that overexpress the tumor biomarker protein EpCAM (epithelial cell adhesion molecule) on their surface.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2014-10
Language
English
Article Type
Article
Keywords

ADHESION MOLECULE; QUANTUM DOTS; MEMBRANE PROCESSES; DNA APTAMERS; LIVING CELLS; CANCER; PROBES; SELECTION; POLYDIACETYLENES; NANOPARTICLES

Citation

CHEMICAL COMMUNICATIONS, v.50, no.82, pp.12329 - 12332

ISSN
1359-7345
DOI
10.1039/c4cc03888f
URI
http://hdl.handle.net/10203/194514
Appears in Collection
CBE-Journal Papers(저널논문)
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