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Mapping mammalian synaptic connectivity

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dc.contributor.authorYook, Chaehyunko
dc.contributor.authorDruckmann, Shaulko
dc.contributor.authorKim, Jinhyunko
dc.date.accessioned2014-08-29-
dc.date.available2014-08-29-
dc.date.created2013-12-16-
dc.date.created2013-12-16-
dc.date.issued2013-12-
dc.identifier.citationCELLULAR AND MOLECULAR LIFE SCIENCES, v.70, no.24, pp.4747 - 4757-
dc.identifier.issn1420-682X-
dc.identifier.urihttp://hdl.handle.net/10203/188592-
dc.description.abstractMapping mammalian synaptic connectivity has long been an important goal of neuroscientists since it is considered crucial for explaining human perception and behavior. Yet, despite enormous efforts, the overwhelming complexity of the neural circuitry and the lack of appropriate techniques to unravel it have limited the success of efforts to map connectivity. However, recent technological advances designed to overcome the limitations of conventional methods for connectivity mapping may bring about a turning point. Here, we address the promises and pitfalls of these new mapping technologies.-
dc.languageEnglish-
dc.publisherSPRINGER BASEL AG-
dc.subjectSTRUCTURED-ILLUMINATION MICROSCOPY-
dc.subjectDE-NOVO MUTATIONS-
dc.subjectAUTISM SPECTRUM DISORDERS-
dc.subjectCENTRAL-NERVOUS-SYSTEM-
dc.subjectCOPY NUMBER VARIATION-
dc.subjectRABIES VIRUS-
dc.subjectTRANSNEURONAL TRACER-
dc.subjectBRAIN CONNECTIVITY-
dc.subjectNEURONAL NETWORKS-
dc.subjectPYRAMIDAL NEURONS-
dc.titleMapping mammalian synaptic connectivity-
dc.typeArticle-
dc.identifier.wosid000327095100008-
dc.identifier.scopusid2-s2.0-84889879194-
dc.type.rimsART-
dc.citation.volume70-
dc.citation.issue24-
dc.citation.beginningpage4747-
dc.citation.endingpage4757-
dc.citation.publicationnameCELLULAR AND MOLECULAR LIFE SCIENCES-
dc.identifier.doi10.1007/s00018-013-1417-y-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.contributor.nonIdAuthorDruckmann, Shaul-
dc.contributor.nonIdAuthorKim, Jinhyun-
dc.type.journalArticleReview-
dc.subject.keywordAuthorSynaptic connectivity-
dc.subject.keywordAuthorBrainbow-
dc.subject.keywordAuthorArray tomography-
dc.subject.keywordAuthormGRASP-
dc.subject.keywordAuthorTrans-synaptic tracer-
dc.subject.keywordAuthorNeurological disorders-
dc.subject.keywordPlusSTRUCTURED-ILLUMINATION MICROSCOPY-
dc.subject.keywordPlusDE-NOVO MUTATIONS-
dc.subject.keywordPlusAUTISM SPECTRUM DISORDERS-
dc.subject.keywordPlusCENTRAL-NERVOUS-SYSTEM-
dc.subject.keywordPlusCOPY NUMBER VARIATION-
dc.subject.keywordPlusRABIES VIRUS-
dc.subject.keywordPlusTRANSNEURONAL TRACER-
dc.subject.keywordPlusBRAIN CONNECTIVITY-
dc.subject.keywordPlusNEURONAL NETWORKS-
dc.subject.keywordPlusPYRAMIDAL NEURONS-
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