Enhanced-throughput production of polymersomes using a parallelized capillary microfluidic device

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dc.contributor.authorKim, Shin-Hyunko
dc.contributor.authorKim, Jin Woongko
dc.contributor.authorKim, Do-Hoonko
dc.contributor.authorHan, Sang-Hoonko
dc.contributor.authorWeitz, David A.ko
dc.date.accessioned2013-08-08T05:43:14Z-
dc.date.available2013-08-08T05:43:14Z-
dc.date.created2013-03-25-
dc.date.created2013-03-25-
dc.date.issued2013-03-
dc.identifier.citationMICROFLUIDICS AND NANOFLUIDICS, v.14, no.3-4, pp.509 - 514-
dc.identifier.issn1613-4982-
dc.identifier.urihttp://hdl.handle.net/10203/174522-
dc.description.abstractWe report a parallelized capillary microfluidic device for enhanced production rate of monodisperse polymersomes. This device consists of four independent capillary microfluidic devices, operated in parallel; each device produces monodisperse water-in-oil-in-water (W/O/W) double-emulsion drops through a single-step emulsification. During generation of the double-emulsion drops, the innermost water drop is formed first and it triggers a breakup of the middle oil phase over wide range of flow rates; this enables robust and stable formation of the double-emulsion drops in all drop makers of the parallelized device. Double-emulsion drops are transformed to polymersomes through a dewetting of the amphiphile-laden middle oil phase on the surface of the innermost water drop, followed by the subsequent separation of the oil drop. Therefore, we can make polymersomes with a production rate enhanced by a factor given by the number of drop makers in the parallelized device.-
dc.languageEnglish-
dc.publisherSPRINGER HEIDELBERG-
dc.subjectMONODISPERSE DOUBLE EMULSIONS-
dc.subjectMICROPARTICLES-
dc.subjectJANUS-
dc.subjectFABRICATION-
dc.subjectPARTICLES-
dc.subjectSHELLS-
dc.subjectPERMEABILITY-
dc.subjectGENERATION-
dc.subjectDROPLETS-
dc.titleEnhanced-throughput production of polymersomes using a parallelized capillary microfluidic device-
dc.typeArticle-
dc.identifier.wosid000315299100010-
dc.identifier.scopusid2-s2.0-84878607025-
dc.type.rimsART-
dc.citation.volume14-
dc.citation.issue3-4-
dc.citation.beginningpage509-
dc.citation.endingpage514-
dc.citation.publicationnameMICROFLUIDICS AND NANOFLUIDICS-
dc.identifier.doi10.1007/s10404-012-1069-5-
dc.contributor.localauthorKim, Shin-Hyun-
dc.contributor.nonIdAuthorKim, Jin Woong-
dc.contributor.nonIdAuthorKim, Do-Hoon-
dc.contributor.nonIdAuthorHan, Sang-Hoon-
dc.contributor.nonIdAuthorWeitz, David A.-
dc.type.journalArticleArticle-
dc.subject.keywordAuthorMicrofluidics-
dc.subject.keywordAuthorPolymersomes-
dc.subject.keywordAuthorEmulsions-
dc.subject.keywordAuthorMicrocapsules-
dc.subject.keywordAuthorParallelization-
dc.subject.keywordPlusMONODISPERSE DOUBLE EMULSIONS-
dc.subject.keywordPlusMICROPARTICLES-
dc.subject.keywordPlusJANUS-
dc.subject.keywordPlusFABRICATION-
dc.subject.keywordPlusPARTICLES-
dc.subject.keywordPlusSHELLS-
dc.subject.keywordPlusPERMEABILITY-
dc.subject.keywordPlusGENERATION-
dc.subject.keywordPlusDROPLETS-
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CBE-Journal Papers(저널논문)
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