DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jongshin | ko |
dc.contributor.author | Woo, Se Joon | ko |
dc.contributor.author | Ahn, Jeeyun | ko |
dc.contributor.author | Park, Ki Ho | ko |
dc.contributor.author | Chung, Hum | ko |
dc.contributor.author | Park, Kyu Hyung | ko |
dc.date.accessioned | 2013-08-08T05:30:24Z | - |
dc.date.available | 2013-08-08T05:30:24Z | - |
dc.date.created | 2013-07-29 | - |
dc.date.created | 2013-07-29 | - |
dc.date.created | 2013-07-29 | - |
dc.date.issued | 2012-11 | - |
dc.identifier.citation | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, v.32, no.10, pp.2052 - 2060 | - |
dc.identifier.issn | 0275-004X | - |
dc.identifier.uri | http://hdl.handle.net/10203/174469 | - |
dc.description.abstract | Purpose: To analyze the long-term changes of peripapillary retinal nerve fiber layer (RNFL) thickness before and after panretinal photocoagulation (PRP) in patients with severe diabetic retinopathy. Methods: In this retrospective observational case series, we reviewed the records of 46 patients (68 eyes) with severe diabetic retinopathy, who were treated with PRP and could be followed for more than 6 months. Peripapillary RNFL thickness and foveal thickness were measured at baseline, 3-month intervals until 1 year post-PRP, and 6- to 12-month intervals after 1 year post-PRP using optical coherence tomography. Long-term changes of peripapillary RNFL thickness and foveal thickness as well as the correlation between the two parameters were analyzed. Results: The average RNFL thickness (360 degrees measurement) decreased significantly from 108.4 mu m to 103.5 mu m at 2 years post-PRP. The average RNFL thickness increased slightly during the initial 3 months post-PRP and thereafter gradually decreased, showing statistically significant reductions at 2 years post-PRP (false discovery rate adjusted P = 0.0051). The superior and inferior quadrant RNFL thicknesses were significantly decreased at 2 years post-PRP (false discovery rate adjusted P = 0.0119 and 0.0051, respectively). The decrease in the nasal quadrant RNFL thickness showed borderline significance at 2 years post-PRP (false discovery rate adjusted P = 0.0854). However, there was no significant decrease in RNFL thickness for the temporal quadrant at any follow-up time. In addition, there was no significant difference in the foveal thickness. But, the pattern of temporal changes in foveal thickness showed a similar pattern with that of temporal RNFL thickness. Conclusion: This study shows that average RNFL thickness after PRP undergoes early thickening and subsequent progressive thinning throughout the 2 years post-PRP. This temporal change varies according to the peripapillary RNFL quadrant. Our results also indicate that temporal RNFL and foveal thickness have a similar pattern of long-term change after PRP. RETINA 32: 2052-2060, 2012 | - |
dc.language | English | - |
dc.publisher | LIPPINCOTT WILLIAMS WILKINS | - |
dc.subject | LASER PHOTOCOAGULATION | - |
dc.subject | GLAUCOMATOUS EYES | - |
dc.subject | REPRODUCIBILITY | - |
dc.subject | DAMAGE | - |
dc.subject | OCT | - |
dc.title | LONG-TERM TEMPORAL CHANGES OF PERIPAPILLARY RETINAL NERVE FIBER LAYER THICKNESS BEFORE AND AFTER PANRETINAL PHOTOCOAGULATION IN SEVERE DIABETIC RETINOPATHY | - |
dc.type | Article | - |
dc.identifier.wosid | 000310520400010 | - |
dc.identifier.scopusid | 2-s2.0-84871347875 | - |
dc.type.rims | ART | - |
dc.citation.volume | 32 | - |
dc.citation.issue | 10 | - |
dc.citation.beginningpage | 2052 | - |
dc.citation.endingpage | 2060 | - |
dc.citation.publicationname | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | - |
dc.identifier.doi | 10.1097/IAE.0b013e3182562000 | - |
dc.contributor.localauthor | Kim, Jongshin | - |
dc.contributor.nonIdAuthor | Woo, Se Joon | - |
dc.contributor.nonIdAuthor | Ahn, Jeeyun | - |
dc.contributor.nonIdAuthor | Park, Ki Ho | - |
dc.contributor.nonIdAuthor | Chung, Hum | - |
dc.contributor.nonIdAuthor | Park, Kyu Hyung | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | long-term | - |
dc.subject.keywordAuthor | retinal nerve fiber thickness | - |
dc.subject.keywordAuthor | panretinal photocoagulation | - |
dc.subject.keywordAuthor | diabetic retinopathy | - |
dc.subject.keywordPlus | LASER PHOTOCOAGULATION | - |
dc.subject.keywordPlus | GLAUCOMATOUS EYES | - |
dc.subject.keywordPlus | REPRODUCIBILITY | - |
dc.subject.keywordPlus | DAMAGE | - |
dc.subject.keywordPlus | OCT | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.