DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Hyun Min | ko |
dc.contributor.author | Kim, Kwang Joon | ko |
dc.contributor.author | Lee, Hye-Jeong | ko |
dc.contributor.author | Yu, Hee Tae | ko |
dc.contributor.author | Moon, Jae Hoon | ko |
dc.contributor.author | Kang, Eun Seok | ko |
dc.contributor.author | Cha, Bong Soo | ko |
dc.contributor.author | Lee, Hyun Chul | ko |
dc.contributor.author | Lee, Byung-Wan | ko |
dc.contributor.author | Kim, Young Jin | ko |
dc.date.accessioned | 2013-03-13T04:26:47Z | - |
dc.date.available | 2013-03-13T04:26:47Z | - |
dc.date.created | 2013-01-08 | - |
dc.date.created | 2013-01-08 | - |
dc.date.issued | 2012-07 | - |
dc.identifier.citation | CARDIOVASCULAR DIABETOLOGY, v.11 | - |
dc.identifier.issn | 1475-2840 | - |
dc.identifier.uri | http://hdl.handle.net/10203/104461 | - |
dc.description.abstract | Background: We used cardiovascular magnetic resonance (CMR) to investigate the association between epicardial adipose tissue (EAT) thickness and silent myocardial ischemia, as well as coronary artery stenosis, in asymptomatic type 2 diabetic patients. Methods: The study included 100 type 2 diabetic subjects (51 male and 49 female; mean age: 56 +/- 7 years). Silent myocardial ischemia, as determined by CMR, was defined as evidence of inducible ischemia or myocardial infarction. Signal reduction or stenosis of >= 50% in the vessel diameter was used as the criteria for significant coronary artery stenosis on coronary magnetic resonance (MR) angiography. Results: EAT thickness was positively correlated with body mass index (BMI), waist-to-hip ratio, systolic blood pressure, postprandial glucose, fasting/postprandial triglyceride (TG), serum glycated hemoglobin (HbA1c) level, and homeostasis model assessment of insulin resistance (HOMA-IR) score. Significant coronary artery stenosis was found in 24 patients, while 14 patients had silent myocardial ischemia in CMR (1 with silent myocardial infarction, 11 with inducible ischemia, and 2 with both). EAT thickness was greater in patients who had coronary artery stenosis (13.0 +/- 2.6 mm vs. 11.5 +/- 2.1 mm, p = 0.01), but did not differ between the subjects with or without silent myocardial ischemia on CMR images (12.8 +/- 2.1 vs. 11.7 +/- 2.3 mm, p = 0.11). Multivariate logistic regression analysis indicated that EAT thickness was an independent indicator for significant coronary artery stenosis after adjusting for traditional risk factors (OR 1.403, p = 0.026). Conclusions: Increased EAT thickness assessed by CMR is an independent risk factor for significant coronary artery stenosis in asymptomatic type 2 diabetes. However, EAT thickness was not associated with silent myocardial ischemia. | - |
dc.language | English | - |
dc.publisher | BIOMED CENTRAL LTD | - |
dc.subject | METABOLIC SYNDROME | - |
dc.subject | COMPUTED-TOMOGRAPHY | - |
dc.subject | FAT VOLUME | - |
dc.subject | DISEASE | - |
dc.subject | ATHEROSCLEROSIS | - |
dc.subject | EXPRESSION | - |
dc.subject | HEART | - |
dc.subject | MRI | - |
dc.subject | FEASIBILITY | - |
dc.subject | ADIPONECTIN | - |
dc.title | Epicardial adipose tissue thickness is an indicator for coronary artery stenosis in asymptomatic type 2 diabetic patients: its assessment by cardiac magnetic resonance | - |
dc.type | Article | - |
dc.identifier.wosid | 000309126500001 | - |
dc.identifier.scopusid | 2-s2.0-84866326744 | - |
dc.type.rims | ART | - |
dc.citation.volume | 11 | - |
dc.citation.publicationname | CARDIOVASCULAR DIABETOLOGY | - |
dc.identifier.doi | 10.1186/1475-2840-11-83 | - |
dc.contributor.localauthor | Yu, Hee Tae | - |
dc.contributor.nonIdAuthor | Kim, Hyun Min | - |
dc.contributor.nonIdAuthor | Kim, Kwang Joon | - |
dc.contributor.nonIdAuthor | Lee, Hye-Jeong | - |
dc.contributor.nonIdAuthor | Moon, Jae Hoon | - |
dc.contributor.nonIdAuthor | Kang, Eun Seok | - |
dc.contributor.nonIdAuthor | Cha, Bong Soo | - |
dc.contributor.nonIdAuthor | Lee, Hyun Chul | - |
dc.contributor.nonIdAuthor | Lee, Byung-Wan | - |
dc.contributor.nonIdAuthor | Kim, Young Jin | - |
dc.description.isOpenAccess | Y | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Epicardial adipose tissue | - |
dc.subject.keywordAuthor | Cardiovascular magnetic resonance | - |
dc.subject.keywordAuthor | Silent ischemia | - |
dc.subject.keywordAuthor | Coronary artery stenosis | - |
dc.subject.keywordAuthor | Type 2 diabetes | - |
dc.subject.keywordPlus | METABOLIC SYNDROME | - |
dc.subject.keywordPlus | COMPUTED-TOMOGRAPHY | - |
dc.subject.keywordPlus | FAT VOLUME | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | HEART | - |
dc.subject.keywordPlus | MRI | - |
dc.subject.keywordPlus | FEASIBILITY | - |
dc.subject.keywordPlus | ADIPONECTIN | - |
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