Designed pneumatic valve actuators for controlled droplet breakup and generation

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The dynamic breakup of emulsion droplets was demonstrated in double-layered microfluidic devices equipped with designed pneumatic actuators. Uniform emulsion droplets, produced by shearing at a T-junction, were broken into smaller droplets when they passed downstream through constrictions formed by a pneumatically actuated valve in the upper control layer. The valve-assisted droplet breakup was significantly affected by the shape and layout of the control valves on the emulsion flow channel. Interestingly, by actuating the pneumatic valve immediately above the T-junction, the sizes of the emulsion droplets were controlled precisely in a programmatic manner that produced arrays of uniform emulsion droplets in various sizes and dynamic patterns.
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2010-01
Language
English
Article Type
Article
Keywords

ON-A-CHIP; PROTEIN CRYSTALLIZATION; DIGITAL MICROFLUIDICS; NANOLITER PLUGS; SINGLE CELLS; FLOW; DEVICES; MICRODROPLETS; CHANNELS; COALESCENCE

Citation

LAB ON A CHIP, v.10, no.4, pp.456 - 461

ISSN
1473-0197
DOI
10.1039/b915596a
URI
http://hdl.handle.net/10203/100030
Appears in Collection
CBE-Journal Papers(저널논문)
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