Reactions of Phosphites with Nitroalkene Derivatives: Syntheses of $\Beta$-Keto Phosphonates and $\alpha$-Cyanoalkylphosphonates

Abstract

The addition of phosphite derivatives 1 to nitroalkenes 2 afforded alpha-phosphoryl nitronates which, on treatment MCPBA, were converted beta-keto phosphonates 3. A versatile reaction conditions to generate alpha-phosphoryl nitronates were examined. alpha-Cyanoalkylphosphonates 6 were prepared from the diethyl trimethylsilyl phosphite (DTSP) 1c with nitroalkenes 2 and followed by reduction.