Continuous glutamate production using an immobilized whole-cell system

For the purpose of saving energy and raw materials required in glutamate fermentation, an immobilized whole-cell system was prepared, and its performance in a continuous reactor system was evaluated. Corynebacterium glutamicum (a mutant strain of ATCC 13058) whole cell was immobilized in kappa -carrageenan matrix, and the gel structure was strengthened by treatment with a hardening agent. The effect of the dilution rate on glutamate production and operational stability were investigated. The performance of the continuous whole-cell reactor system was evaluated by measuring glutamate productivity for a period of 30 days; it was found to be far superior to the performance of conventional batch reactor systems using free cells.
Publisher
Wiley-VCH Verlag
Issue Date
1982-10
Language
ENG
Citation

BIOTECHNOLOGY AND BIOENGINEERING, v.24, no.10, pp.2167 - 2174

ISSN
0006-3592
URI
http://hdl.handle.net/10203/64803
Appears in Collection
BS-Journal Papers(저널논문)
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