DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chang, Ho Nam | ko |
dc.contributor.author | ik-keun yoo | ko |
dc.contributor.author | beon soo kim | ko |
dc.date.accessioned | 2013-02-25T18:37:19Z | - |
dc.date.available | 2013-02-25T18:37:19Z | - |
dc.date.created | 2012-02-06 | - |
dc.date.created | 2012-02-06 | - |
dc.date.issued | 1994 | - |
dc.identifier.citation | BIOTECHNOLOGY ADVANCES, v.12, no.3, pp.467 - 487 | - |
dc.identifier.issn | 0734-9750 | - |
dc.identifier.uri | http://hdl.handle.net/10203/64390 | - |
dc.description.abstract | Enhancement of productivity of a bioprocess necessitates continuous operation of bioreactors with high biomass concentrations than are possible in conventional batch, fed-batch or continuous modes of culture. Membrane-based cell recycle has been effectively used to maintain high cell concentrations in bioreactors. This review compares membrane-based cell recycle operation with other such high density cell culture systems as immobilized cell reactors and reactors with cell recycle by centrifugation or gravity sedimentation. A theoretical of production of primary and secondary metabolites in membrane-based recycle systems is presented. Operation of this type of system is discussed with examples from aerobic and anaerobic fermentations. | - |
dc.language | English | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.subject | HOLLOW-FIBER BIOREACTOR | - |
dc.subject | PRODUCTIVITY ETHANOL FERMENTATIONS | - |
dc.subject | HIGH-CONCENTRATION CULTIVATION | - |
dc.subject | CROSS-FLOW FILTRATION | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | CLOSTRIDIUM-ACETOBUTYLICUM | - |
dc.subject | SACCHAROMYCES-CEREVISIAE | - |
dc.subject | RETENTION CULTURE | - |
dc.subject | ZYMOMONAS-MOBILIS | - |
dc.subject | ACID PRODUCTION | - |
dc.title | HIGH-DENSITY CELL-CULTURE BY MEMBRANE-BASED CELL RECYCLE | - |
dc.type | Article | - |
dc.identifier.wosid | A1994NZ71700001 | - |
dc.identifier.scopusid | 2-s2.0-0028110779 | - |
dc.type.rims | ART | - |
dc.citation.volume | 12 | - |
dc.citation.issue | 3 | - |
dc.citation.beginningpage | 467 | - |
dc.citation.endingpage | 487 | - |
dc.citation.publicationname | BIOTECHNOLOGY ADVANCES | - |
dc.identifier.doi | 10.1016/0734-9750(94)90020-5 | - |
dc.contributor.localauthor | Chang, Ho Nam | - |
dc.contributor.nonIdAuthor | ik-keun yoo | - |
dc.contributor.nonIdAuthor | beon soo kim | - |
dc.type.journalArticle | Review | - |
dc.subject.keywordAuthor | HIGH DENSITY CELL CULTURE | - |
dc.subject.keywordAuthor | CELL RECYCLE | - |
dc.subject.keywordAuthor | CELL RETENTION | - |
dc.subject.keywordAuthor | BIOREACTORS | - |
dc.subject.keywordPlus | HOLLOW-FIBER BIOREACTOR | - |
dc.subject.keywordPlus | PRODUCTIVITY ETHANOL FERMENTATIONS | - |
dc.subject.keywordPlus | HIGH-CONCENTRATION CULTIVATION | - |
dc.subject.keywordPlus | CROSS-FLOW FILTRATION | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | CLOSTRIDIUM-ACETOBUTYLICUM | - |
dc.subject.keywordPlus | SACCHAROMYCES-CEREVISIAE | - |
dc.subject.keywordPlus | RETENTION CULTURE | - |
dc.subject.keywordPlus | ZYMOMONAS-MOBILIS | - |
dc.subject.keywordPlus | ACID PRODUCTION | - |
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