DC Field | Value | Language |
---|---|---|
dc.contributor.author | Hsing, Li-Chang | ko |
dc.contributor.author | Kim, Ji Yeun | ko |
dc.contributor.author | Kwon, Ji-Soo | ko |
dc.contributor.author | Shin, Eui-Cheol | ko |
dc.contributor.author | Kim, Sung-Han | ko |
dc.date.accessioned | 2019-10-22T05:20:07Z | - |
dc.date.available | 2019-10-22T05:20:07Z | - |
dc.date.created | 2019-10-22 | - |
dc.date.created | 2019-10-22 | - |
dc.date.created | 2019-10-22 | - |
dc.date.issued | 2019-09 | - |
dc.identifier.citation | INFECTION AND CHEMOTHERAPY, v.51, no.3, pp.310 - 314 | - |
dc.identifier.issn | 2093-2340 | - |
dc.identifier.uri | http://hdl.handle.net/10203/268023 | - |
dc.description.abstract | The clinical benefit of adjuvant intravenous immunoglobulin (WIG) therapy is controversial in immunocompromised patients with severe varicella. A twenty-one-year-old woman who had received a kidney transplant one year earlier presented with fever and generalized rash for 5 days. Initial immunoglobulin M (IgM) and IgG for varicella zoster virus (VZV) were negative; however, the patient was diagnosed with varicella with fulminant hepatitis because VZV-specific PCR from skin vesicles and blood was positive. The patient received intravenous acyclovir and 5-day IVIG. The decline of plasma viral load was steeper (beta coefficient-0.446) during WIG therapy than after the therapy (beta coefficient -0.123) (P= 0.04), while VZV glycoprotein IgG titers and VZV-specific T cell responses were not detected during the 5-day WIG therapy. The patient improved without any complications. This case provides an experimental evidence that adjuvant IVIG can significantly reduce viral load in immunocompromised patients with severe varicella. | - |
dc.language | English | - |
dc.publisher | KOREAN SOC CHEMOTHERAPY | - |
dc.title | Successful treatment of fulminant hepatitis due to varicella zoster virus using immunoglobulin in a kidney transplant patient | - |
dc.type | Article | - |
dc.identifier.scopusid | 2-s2.0-85074338674 | - |
dc.type.rims | ART | - |
dc.citation.volume | 51 | - |
dc.citation.issue | 3 | - |
dc.citation.beginningpage | 310 | - |
dc.citation.endingpage | 314 | - |
dc.citation.publicationname | INFECTION AND CHEMOTHERAPY | - |
dc.identifier.doi | 10.3947/ic.2019.51.3.310 | - |
dc.contributor.localauthor | Shin, Eui-Cheol | - |
dc.contributor.nonIdAuthor | Hsing, Li-Chang | - |
dc.contributor.nonIdAuthor | Kim, Ji Yeun | - |
dc.contributor.nonIdAuthor | Kim, Sung-Han | - |
dc.description.isOpenAccess | Y | - |
dc.type.journalArticle | Article | - |
dc.subject.keywordAuthor | Varicella zoster virus | - |
dc.subject.keywordAuthor | Fatal hepatitis | - |
dc.subject.keywordAuthor | Intravenous immunoglobulin | - |
dc.subject.keywordPlus | ADULT | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | ACYCLOVIR | - |
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