Cu(OTf)(2)-Promoted 1,4-Addition of Alkyl Bromides to Dehydroalanine

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Zn/Cu(OTf)(2)-mediated addition of alkyl bromides to dehydroalanine (Dha) derivatives including dipeptides and tripeptides in good to high yields under an aqueous medium was developed. This protocol allows selective and biocompatible access to various amino acid units from Dha derivatives.
Publisher
AMER CHEMICAL SOC
Issue Date
2019-04
Language
English
Article Type
Article
Citation

JOURNAL OF ORGANIC CHEMISTRY, v.84, no.7, pp.4558 - 4565

ISSN
0022-3263
DOI
10.1021/acs.joc.9b00369
URI
http://hdl.handle.net/10203/261730
Appears in Collection
CH-Journal Papers(저널논문)
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