A dual-response sensor based on NBD for the highly selective determination of sulfide in living cells and zebrafish

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A dual chemosensor, 1-NO2, based on the combination of 4-chloro-7-nitrobenzofurazan (NBD) and 1-(2-hydroxyethyl)piperazine, was applied for the detection of sulfide. Chemosensor 1-NO2 could detect sulfide through fluorescence turn-off and color change from orange to pink-red. The sensing mechanism and structure of 1-NO2 with S2- were demonstrated using Job's plot, ESI-MS analysis and theoretical calculations. In addition, 1-NO2 as a sulfide detector could be used in living organisms (HeLa cells and zebrafish).
Publisher
ROYAL SOC CHEMISTRY
Issue Date
2019-03
Language
English
Article Type
Article
Citation

NEW JOURNAL OF CHEMISTRY, v.43, no.10, pp.4029 - 4035

ISSN
1144-0546
DOI
10.1039/c8nj06352d
URI
http://hdl.handle.net/10203/253972
Appears in Collection
CH-Journal Papers(저널논문)
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