Pioneering Effects and Enhanced Neurite Complexity of Primary Hippocampal Neurons on Hierarchical Neurotemplated Scaffolds

Cited 2 time in webofscience Cited 0 time in scopus
  • Hit : 217
  • Download : 0
In this work, the use of scaffolds is reported, templated from live neurons as an advanced culture platform for primary neurons. Hippocampal neurons cultured on neurotemplated scaffolds exhibit an affinity for templated somas, revealing a preference for micrometric structures amidst nanotopographical features. It is also reported, for the first time, that neurite complexity can be topographically controlled by increasing the density of nanometric features on neurotemplated scaffolds. Neurotemplated scaffolds are versatile, hierarchical topographies that feature biologically relevant structures, in both form and scale, and capture the true complexity of an in vivo environment. The introduction and implementation of neurotemplated scaffolds is sure to advance research in the fields of neurodevelopment, network development, and neuroregeneration.
Publisher
WILEY
Issue Date
2018-09
Language
English
Article Type
Article
Citation

ADVANCED HEALTHCARE MATERIALS, v.7, no.18

ISSN
2192-2640
DOI
10.1002/adhm.201800289
URI
http://hdl.handle.net/10203/246222
Appears in Collection
CH-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 2 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0