Overcoming Depression by Inhibition of Neural Burst Firing

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The N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine has been found to have rapid and long-lasting antidepressive effects. Two elegant studies from Hailan Hu's laboratory (Cui et al., 2018; Yang et al., 2018) showed that ketamine blocks burst firing of neurons in the lateral habenula (LHb), rapidly relieving symptoms of depression.
Publisher
CELL PRESS
Issue Date
2018-06
Language
English
Article Type
Editorial Material
Keywords

LATERAL HABENULA; CA2+ CHANNELS; KETAMINE

Citation

NEURON, v.98, no.5, pp.878 - 879

ISSN
0896-6273
DOI
10.1016/j.neuron.2018.05.032
URI
http://hdl.handle.net/10203/244553
Appears in Collection
BS-Journal Papers(저널논문)
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