Reductive Carbocyclization of Homoallylic Alcohols to syn-Cyclobutanes by a Boron-Catalyzed Dual Ring-Closing Pathway

Cited 26 time in webofscience Cited 0 time in scopus
  • Hit : 400
  • Download : 0
The organoborane-catalyzed reductive carbocyclization of homoallylic alcohols has been developed by using hydrosilanes as reducing reagents to provide a range of 1,2-disubstituted arylcyclobutanes. The reaction proceeds in a cis-selective manner with high efficiency under mild conditions. Mechanistic studies, including deuterium scrambling and Hammett studies, and DFT calculations, suggest a dual ring-closing pathway.
Publisher
WILEY-V C H VERLAG GMBH
Issue Date
2018-03
Language
English
Article Type
Article
Keywords

ORGANIC-SYNTHESIS; COPPER(I)-CATALYZED REACTION; SUBSTITUENT CONSTANTS; METHANE MONOOXYGENASE; MEDICINAL CHEMISTRY; DERIVATIVES; CATIONS; PHOTOCYCLOADDITIONS; REARRANGEMENTS; HYDROXYLATION

Citation

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.57, no.10, pp.2692 - 2696

ISSN
1433-7851
DOI
10.1002/anie.201713285
URI
http://hdl.handle.net/10203/240702
Appears in Collection
CH-Journal Papers(저널논문)
Files in This Item
There are no files associated with this item.
This item is cited by other documents in WoS
⊙ Detail Information in WoSⓡ Click to see webofscience_button
⊙ Cited 26 items in WoS Click to see citing articles in records_button

qr_code

  • mendeley

    citeulike


rss_1.0 rss_2.0 atom_1.0