Mismatch DNA-specific enzymatic cleavage employed in a new method for the electrochemical detection of genetic mutations
Utilizing enzymatic mismatched DNA-specific cleavage and electrocatalytic signaling, a new electrochemical method for the detection of DNA mutations was developed and successfully applied to detect various mutations in the BRCA1 gene.
- Publisher
- ROYAL SOC CHEMISTRY
- Issue Date
- 2009-06
- Language
- English
- Article Type
- Article
- Keywords
SINGLE-BASE EXTENSION; ZIP-CODE MICROARRAY; HNF-1-ALPHA MUTATIONS; LIGASE; POLYMORPHISM; BRCA1; ASSAY; SNPS; OLIGONUCLEOTIDE; HYBRIDIZATION
- Citation
CHEMICAL COMMUNICATIONS, no.28, pp.4230 - 4232
- ISSN
- 1359-7345
- Appears in Collection
- CBE-Journal Papers(저널논문)
- Files in This Item
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